Recent insight into potential acute respiratory distress syndrome

被引:7
作者
Amin, Zulkifli [1 ]
Rahmawati, Fitriana N. [1 ]
机构
[1] Univ Indonesia, Cipto Mangunkusumo Hosp, Fac Med, Dept Internal Med, Jakarta, Indonesia
关键词
GLYCATION END-PRODUCTS; ALVEOLAR FLUID CLEARANCE; SOLUBLE RECEPTOR; RECRUITMENT MANEUVER; PLASMA-LEVELS; INFLAMMATION; BIOMARKERS; MARKER; INJURY; INTERLEUKIN-6;
D O I
10.15537/smj.2017.4.15843
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung injury, characterized by increased pulmonary capillary endothelial cells and alveolar epithelial cells permeability leading to respiratory failure in the absence of cardiac failure. Despite recent advances in treatments, the overall mortality because of ARDS remains high. Biomarkers may help to diagnose, predict the severity, development, and outcome of ARDS in order to improve patient care and decrease morbidity and mortality. This review will focus on soluble receptor for advanced glycation end-products, soluble tumor necrosis factor-receptor 1, Interluken-6 (IL-6), IL-8, and plasminogen activator inhibitor-1, which have a greater potential based on recent studies.
引用
收藏
页码:344 / 349
页数:6
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