Using invertebrate model organisms for neuroscience research and training: an opportunity for Africa

被引:5
作者
Balogun, Wasiu Gbolahan [1 ]
Cobham, Ansa Emmanuel [2 ,3 ]
Amin, Abdulbasit [4 ,5 ]
Seeni, Azman [1 ,6 ]
机构
[1] Univ Sains Malaysia, Adv Med & Dent Inst, Bertam 13200, Penang, Malaysia
[2] Univ Calabar, Dept Anat, Fac Basic Med Sci, Calabar, Nigeria
[3] Monash Univ, Sch Biol Sci, Melbourne, Vic 3800, Australia
[4] Univ Ilorin, Dept Physiol, Fac Basic Med Sci, Ilorin, Nigeria
[5] Inst Gulbenkian Ciencias, Rua Quinta Grande 6, P-2780156 Lisbon, Portugal
[6] Natl Inst Biotechnol Malaysia, Malaysian Inst Pharmaceut & Nutraceut, Gelugor 11700, Pulau Pinang, Malaysia
关键词
Invertebrates; Neuroscience; Africa; Modelling; Research; Training; DROSOPHILA-MELANOGASTER; BIOMEDICAL-RESEARCH; ACETYLCHOLINESTERASE; IMMUNOREACTIVITY; ORGANIZATION; ORIENTATION; TOXICITY; BEHAVIOR; BEETLES; PEPTIDE;
D O I
10.1007/s11011-018-0250-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Africa is faced with an increasing underrepresentation of her research progress in many fields of science including neuroscience. This underrepresentation stems from the very low investments directed towards research by African governments as these are thought to be high-priced. Scientists and researchers within the continent are left to compete highly for the very limited research grants or choose to fund research from their personal purse. Therefore, presenting a need for all possible strategies to make science and research approaches more affordable in Africa. This paper presents one of such strategy, which advocates the use of invertebrate animal models for neuroscience research in place of the commonly used vertebrate models. Invertebrates are cheaper, more available and easy to handle options and their use is on the rise, even in the developed societies of the world. Here, we investigate the current state of invertebrate neuroscience research in Africa looking at countries and institutions conducting neuroscience research with invertebrates and their publication output. We discuss the factors which impede invertebrate neuroscience research in Africa like lack of research infrastructure and adequate expert scientists and conclude by suggesting solutions to these challenges.
引用
收藏
页码:1431 / 1441
页数:11
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