GenCompass: a universal system for analysing gene expression for any genome

被引:2
作者
Luscombe, NM
Babu, MM
机构
[1] Yale Univ, Dept Mol Biophys & Biochem, New Haven, CT 06520 USA
[2] MRC, Mol Biol Lab, Cambridge CB2 2QH, England
关键词
D O I
10.1016/j.tibtech.2004.08.013
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Microarrays have become indispensable tools for studying the gene expression of particular organisms on a genomic scale. However, despite its widespread use, there are several draw-backs to the current technology. First, it requires prior knowledge of the DNA sequence encoded in the organism of interest, and second, chips must be designed specifically for each genome, greatly increasing the initial cost incurred in manufacturing the arrays.
引用
收藏
页码:552 / 555
页数:4
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