4 Ds in health research-working together toward rapid precision medicine

被引：6

作者：

Niederberger, Ellen ^{[1
]}

Parnham, Michael J. ^{[2
,3
]}

Maas, Jochen ^{[4
]}

Geisslinger, Gerd ^{[1
,2
,3
]}

机构：

[1] Klinikum Goethe Univ Frankfurt, Pharmazentrum Frankfurt ZAFES, Inst Klin Pharmakol, Frankfurt, Germany

[2] Fraunhofer Inst Mol Biol & Appl Ecol IME, Branch Translat Med & Pharmacol TMP, Frankfurt, Germany

[3] Fraunhofer Cluster Excellence Immune Mediated Dis, Frankfurt, Germany

[4] Sanofi Aventis Deutschland GmbH, Ind Pk Hochst, Frankfurt, Germany

来源：

EMBO MOLECULAR MEDICINE | 2019年 / 11卷 / 11期

关键词：

D O I：

10.15252/emmm.201910917

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Patient therapy is based mainly on a combination of diagnosis, suitable monitoring or support devices and drug treatment and is usually employed for a pre-existing disease condition. Therapy remains predominantly symptom-based, although it is increasingly clear that individual treatment is possible and beneficial. However, reasonable precision medicine can only be realized with the coordinated use of diagnostics, devices and drugs in combination with extensive databases (4Ds), an approach that has not yet found sufficient implementation. The practical combination of 4Ds in health care is progressing, but several obstacles still hamper their extended use in precision medicine.

引用

页数：7

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