Iodine(III) reagent (ABX-N3)-induced intermolecular anti-Markovnikov hydroazidation of unactivated alkenes

被引：25

作者：

Li, Xiaonan ^{[1
]}

Chen, Pinhong ^{[1
]}

Liu, Guosheng ^{[1
]}

机构：

[1] Univ Chinese Acad Sci, State Key Lab Organometall Chem, Chinese Acad Sci, Ctr Excellence Mol Synth,Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China

来源：

SCIENCE CHINA-CHEMISTRY | 2019年 / 62卷 / 11期

基金：

中国国家自然科学基金;

关键词：

anti-Markovnikov; hydroazidation; iodine(III) reagent (ABX-N-3); unactivated alkenes; METAL-FREE; CATALYZED HYDROAMINATION; OXIDATIVE AMINATION; OLEFINS; ACCESS; DIAZIDATION; AZIDATION; AZIDE; HYDROXYAZIDATION; CARBOAZIDATION;

D O I：

10.1007/s11426-019-9628-9

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Anti-Markovnikov hydroazidation of unactivated alkenes using ABX2014;N-3 as an initiator has been developed at room temperature, wherein hydrogen azide (HN3) acts as both hydrogen and azidating agent. Notably, the HN3 reagent was generated from azidotrimethylsilane (TMSN3) and acetic acid in situ. The reaction itself displays broad substrate scope, good yields and excellent regioselectivities.

引用

页码：1537 / 1541

页数：5

共 60 条

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