Is a foetus developing in a sterile environment?

被引:99
作者
Wassenaar, T. M. [1 ]
Panigrahi, P. [2 ]
机构
[1] Mol Microbiol & Consultants, D-55576 Zotzenheim, Germany
[2] Univ Nebraska Med Ctr, Omaha, NE USA
关键词
amniotic fluid; breast milk; neonatal sepsis; newborn colonization; placenta microbiome; placental microbiome; preterm birth; AMNIOTIC-FLUID; MYCOPLASMA-HOMINIS; PLACENTA HARBORS; DENDRITIC CELLS; PRETERM INFANTS; LACTIC-ACID; HUMAN-MILK; MICROBIOTA; BACTERIA; LACTOBACILLI;
D O I
10.1111/lam.12334
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Novel findings in microbiology question the long-standing paradigm that a healthy pregnancy implies a sterile uterus. It now seems that the placenta is frequently colonized with bacteria, and a placental microbiome has been identified. Recent literature findings are summarized here, and an attempt is made to separate pathological bacterial presence from a naturally occurring microbiome.
引用
收藏
页码:572 / 579
页数:8
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