Antimalarial naphthoquinones from Nepenthes thorelii

被引：124
作者：
Likhitwitayawuid, K [1 ]
Kaewamatawong, R
Ruangrungsi, N
Krungkrai, J
机构：
[1] Chulalongkorn Univ, Fac Pharmaceut Sci, Dept Pharmacognosy, Bangkok 10330, Thailand
[2] Chulalongkorn Univ, Fac Med, Dept Biochem, Bangkok 10330, Thailand
来源：
PLANTA MEDICA | 1998年 / 64卷 / 03期
关键词：
Nepenthes thorelii; Nepenthaceae; naphthoquinone; antimalarial activity;
D O I：
10.1055/s-2006-957417
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Roots of Nepenthes thorelii yielded plumbagin, 2-methylnaphthazarin, octadecyl caffeate, isoshinanolone, and droserone. In addition, seven derivatives were prepared from plumbagin. Each of these natural and semisynthetic compounds was evaluated for in vitro antimalarial potential.
引用
收藏
页码：237 / 241
页数：5
相关论文
共 27 条
[1]  
ADIRUKMI NS, 1994, P ASOMP 8 MAL
[2]  
[Anonymous], 1993, PLANT BOOK PORTABLE
[3]   EPI-ISOSHINANOLONE FROM PLUMBAGO-SCANDENS [J].
BHATTACHARYYA, J ;
DECARVALHO, VR .
PHYTOCHEMISTRY, 1986, 25 (03) :764-765
[4]   THE QUINONES OF NEPENTHES-RAFFLESIANA - THE CRYSTAL-STRUCTURE OF 2,5-DIHYDROXY-3,8-DIMETHOXY-7-METHYLNAPHTHO-1,4-QUINONE (NEPENTHONE-E) AND A SYNTHESIS OF 2,5-DIHYDROXY-3-METHOXY-7-METHYLNAPHTHO-1,4-QUINONE (NEPENTHONE-C) [J].
CANNON, JR ;
LOJANAPIWATNA, V ;
RASTON, CL ;
SINCHAI, W ;
WHITE, AH .
AUSTRALIAN JOURNAL OF CHEMISTRY, 1980, 33 (05) :1073-1093
[5]   IDENTIFICATION OF METHYLNAPHTHAZARIN IN DIOSPYROS SPECIES [J].
FERREIRA, MA ;
AUREACRU.M ;
CORREIAA.A .
PHYTOCHEMISTRY, 1972, 11 (07) :2352-&
[6]   ANNULATION REACTIONS LEADING TO NAPHTHALENE DERIVATIVES - NEW SYNTHESES OF NATURAL 1,2-NAPHTHOQUINONES AND 1,4-NAPHTHOQUINONES [J].
GHERA, E ;
BENDAVID, Y .
JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (18) :3355-3359
[7]   SYNTHESES OF SUBSTITUTED 1,4-NAPHTHOQUINONES BY DIELS-ALDER ADDITION OF METHOXYCYCLOHEXADIENES TO SUBSTITUTED 1,4-BENZOQUINONES [J].
GILES, RGF ;
ROOS, GHP .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1976, (19) :2057-2060
[8]  
HOOKER JD, 1975, FLORA BRIT INDIA, V5
[9]   FLAVONOIDS IN ROOTS OF SOPHORA-PROSTRATA [J].
IINUMA, M ;
OHYAMA, M ;
TANAKA, T .
PHYTOCHEMISTRY, 1995, 38 (02) :539-543
[10]   NAPHTHOQUINONES FROM DIONAEA-MUSCIPULA [J].
KREHER, B ;
NESZMELYI, A ;
WAGNER, H .
PHYTOCHEMISTRY, 1990, 29 (02) :605-606
123