Carboxymethylated cotton for moist wound healing

被引：0

作者：

Parikh, DV

Sachinvala, ND

Calamari, TA

Negulescu, I

机构：

[1] USDA, So Reg Res Ctr, New Orleans, LA 70179 USA

[2] Louisiana State Univ, Baton Rouge, LA 70803 USA

来源：

AATCC REVIEW | 2003年 / 3卷 / 06期

关键词：

carboxymethylation; occlusive dressings; alginate dressings; wound healing;

D O I：

暂无

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Chronic wounds are not easy to heal. Research in wound physiology has shown that healing is accelerated when the wounds are kept moist. While alginate dressings produce accelerated healing, they are expensive. The present work was directed at developing less expensive moist wound dressings from carboxymethylated cotton gauze/nonwovens. These dressings would absorb high amounts of wound exudate similar to alginates. Gauze bandage rolls were modified into highly absorbent, carboxymethylated bandage rolls, eliminating the need for any subsequent converting operation. Carboxymethylation was carried out by treating cotton gauze rolls with caustic and monochloroacetic acid in 90/10 ethanol/water media. Post-treating Na-CM-cotton rolls, upon ion exchange, made it possible to obtain Ca/Na-CM-cotton gauze rolls. Ca/Na-CM-gauze will be competitive with calcium-alginate dressings.

引用

页码：15 / 19

页数：5