Two New Alkaloids from Stemona tuberosa

被引:12
作者
Zhong, Ying [2 ]
Gao, Ying [2 ]
Guo, Qiu-Ping [1 ]
Li, Wei-Min [1 ]
机构
[1] Guangzhou Univ Chinese Med, Coll Chinese Mat Med, Guangzhou Higher Educ Mega Ctr, Guangzhou 510006, Guangdong, Peoples R China
[2] Guangzhou Univ Chinese Med, Res & Dev Ctr New Drugs, Guangzhou 510006, Guangdong, Peoples R China
关键词
D O I
10.1002/hlca.200900134
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Two new alkaloids, named tuberostemoninol A (1) and tuberostemoninol B (2), along with the known compounds tuberostemoninol (3) and bisdehydroneotuberostemonine (4), were isolated from Stemona tuberosa LOUR. The structures were elucidated by means of spectroscopic analyses. including 1D- and 2D-NMR experiments. The four alkaloids 1-4 were analyzed by on-line high-performance liquid chromatography/electrospray-ionization mass spectrometry (HPLC/ESI-MS), and their fragmentation pathways were found to be similar. Compounds 1, 2, and 3 are isomers with the same molecular mass but which eluted at different retention times.
引用
收藏
页码:133 / 138
页数:6
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