Identification, determination and biological evaluation of novel styrene trimer in polystyrene container

被引：9

作者：

Yamada, T ^{[1
]}

Hirano, S ^{[1
]}

Kobayashi, K ^{[1
]}

Sakurai, T ^{[1
]}

Takaki, I ^{[1
]}

Tanaka, M ^{[1
]}

Nagao, Y ^{[1
]}

Azuma, Y ^{[1
]}

Date, K ^{[1
]}

Ohno, K ^{[1
]}

Chiba, M ^{[1
]}

Nobuhara, Y ^{[1
]}

机构：

[1] Nissin Food Prod Co Ltd, Cent Res Inst, Shiga 5250055, Japan

来源：

BUNSEKI KAGAKU | 2000年 / 49卷 / 07期

关键词：

polystyrene products; styrene trimer; 1-phenyl-4-(2-phenylethyl) tetralin; X-ray crystal structure; material and migration test of NST-12; biological evaluation;

D O I：

10.2116/bunsekikagaku.49.493

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The presence of unidentified styrene trimers (NST-12-1 and NST-12-2) was confirmed in the eluted substance of polystyrene. Both compounds were two diastereomers of 1-phenyl-4- (2-phenylethyl) tetralin, which were proved to be the 1,4-cis (NST-12-1) and 1,4-trans (NST-12-2) configuration by instrumental analysis and chemical synthesis. The content and miglation of NST-12 in polystyrene products were determined by GC/MS (SIM). Furthermore, the endocrine-disrupting effects of NST-12 were tested by in vivo and in vitro assays. It appeared that NST-12 has no such effects.

引用

页码：493 / 501

页数：9