Chronic inflammatory demyelinating polyradiculoneuropathy in patients with liver transplantation

被引:22
作者
Echaniz-Laguna, A
Battaglia, F
Ellero, B
Mohr, M
Jaeck, D
机构
[1] Hospices Civils Strasbourg, Dept Neurol, F-67091 Strasbourg, France
[2] Hop Hautepierre, Serv Chirurg Gen & Transplantat, Strasbourg, France
[3] Hospices Civils Strasbourg, Inst Pathol Anat, Strasbourg, France
关键词
alcoholic cirrhosis; chronic inflammatory demyelinating polyradiculoneuropathy; cyclosporine; hepatitis C; liver transplantation;
D O I
10.1002/mus.20086
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report two patients with orthotopic liver transplantation (OLT) who developed a syndrome that fulfilled criteria for definite chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). One patient had OLT because of alcoholic cirrhosis and one following hepatitis C-induced hepatic failure. Both had immunosuppressive therapy, with cyclosporine and prednisolone in one case and tacrolimus in the other case. Treatment with intravenous immune globulin (IVIG) significantly improved the neuropathy in both patients. In patients with OLT developing disabling sensorimotor neuropathies, CIDP should be considered as should the use of potentially beneficial immunosuppressive treatment.
引用
收藏
页码:501 / 504
页数:4
相关论文
共 19 条
[1]   Positive effects of tacrolimus in a case of CIDP [J].
Ahlmén, J ;
Andersen, O ;
Hallgren, G ;
Peilot, B .
TRANSPLANTATION PROCEEDINGS, 1998, 30 (08) :4194-4194
[2]   POLYNEUROPATHY COMPLICATING BONE-MARROW AND SOLID-ORGAN TRANSPLANTATION [J].
AMATO, AA ;
BAROHN, RJ ;
SAHENK, Z ;
TUTSCHKA, PJ ;
MENDELL, JR .
NEUROLOGY, 1993, 43 (08) :1513-1518
[3]  
Barnett MH, 1998, MUSCLE NERVE, V21, P454, DOI 10.1002/(SICI)1097-4598(199804)21:4<454::AID-MUS3>3.0.CO
[4]  
2-8
[5]  
CORNBLATH DR, 1991, NEUROLOGY, V41, P617
[6]   PREDNISONE IMPROVES CHRONIC INFLAMMATORY DEMYELINATING POLYRADICULONEUROPATHY MORE THAN NO TREATMENT [J].
DYCK, PJ ;
OBRIEN, PC ;
OVIATT, KF ;
DINAPOLI, RP ;
DAUBE, JR ;
BARTLESON, JD ;
MOKRI, B ;
SWIFT, T ;
LOW, PA ;
WINDEBANK, AJ .
ANNALS OF NEUROLOGY, 1982, 11 (02) :136-141
[7]   Treatment of chronic inflammatory demyelinating polyneuropathy with interferon-α 2a [J].
Gorson, KC ;
Ropper, AH ;
Clark, BD ;
Dew, RB ;
Simovic, D ;
Allam, G .
NEUROLOGY, 1998, 50 (01) :84-87
[8]   Neurologic complications of liver transplantation in adults [J].
Lewis, MB ;
Howdle, PD .
NEUROLOGY, 2003, 61 (09) :1174-1178
[9]   THE EFFECTS OF PROPHYLACTIC CYCLOSPORINE-A ON EXPERIMENTAL ALLERGIC NEURITIS (EAN) IN THE LEWIS RAT - INDUCTION OF RELAPSING EAN USING LOW-DOSE CYCLOSPORINE-A [J].
MCCOMBE, PA ;
VANDERKREEK, SA ;
PENDER, MP .
JOURNAL OF NEUROIMMUNOLOGY, 1990, 28 (02) :131-140
[10]  
NEGORO K, 1994, MUSCLE NERVE, V17, P1351