One-pot four component synthesis of novel 3-furyl coumarin derivatives

被引：6

作者：

Jalli, Venkata Prasad ^{[1
]}

Krishnamurthy, Suvratha ^{[1
]}

Moriguchi, Tetsuji ^{[1
]}

Tsuge, Akihiko ^{[1
]}

机构：

[1] Kyushu Inst Technol, Dept Appl Chem, Kitakyushu, Fukuoka 8048550, Japan

来源：

JOURNAL OF CHEMICAL SCIENCES | 2016年 / 128卷 / 02期

关键词：

4-chloro-3-formyl coumarin; secondary amines; 3+2] cyclo addition; Multicomponent reaction; X-ray crystallography; HIGHLY FUNCTIONALIZED KETENIMINES; DIMETHYL ACETYLENEDICARBOXYLATE; CYCLOHEXYL ISOCYANIDE; BIOLOGICAL-ACTIVITY; FLUORESCENT DYES; FUROCOUMARINS; CHEMISTRY; TOXICITY;

D O I：

10.1007/s12039-015-1014-8

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Efficient and facile synthesis of 3-furyl coumarin derivatives have been achieved by reaction of 4-chloro-3-formylcoumarin, secondary amines, dialkyl acetylenedicarboxylates and diversely substituted isocyanides using four component, one-pot reaction. All the products were isolated as yellow color fluorescent solids by column chromatography in quantitative yield and characterized with H-1 NMR, C-13 NMR, IR and FAB mass.

引用

页码：217 / 226

页数：10

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