Improved delivery of sinus irrigations after middle turbinate resection during endoscopic sinus surgery

被引:27
作者
Kidwai, Sarah M. [1 ]
Parasher, Arjun K. [1 ]
Khan, Mohemmed N. [1 ]
Eloy, Jean Anderson [2 ,3 ,4 ,5 ]
Del Signore, Anthony [6 ]
Iloreta, Alfred Marc [1 ]
Govindaraj, Satish [1 ]
机构
[1] Mt Sinai Med Ctr, Dept Otolaryngol Head & Neck Surg, Annenberg 10th Floor,One Gustave L Levy Pl, New York, NY 10029 USA
[2] Rutgers New Jersey Med Sch, Dept Otolaryngol Head & Neck Surg, Newark, NJ USA
[3] Rutgers New Jersey Med Sch, Neurol Inst New Jersey, Ctr Skull Base & Pituitary Surg, Newark, NJ USA
[4] Rutgers New Jersey Med Sch, Dept Neurol Surg, Newark, NJ USA
[5] Rutgers New Jersey Med Sch, Dept Ophthalmol & Visual Sci, Newark, NJ USA
[6] Beth Israel Hosp, Dept Otolaryngol Head & Neck Surg, New York, NY USA
关键词
sinus irrigation; middle turbinate resection; MTR; topical delivery; delivery technique; FESS; endoscopic sinus surgery; ESS; PARANASAL SINUSES; CHRONIC RHINOSINUSITIS; DRUG-DELIVERY; DEPOSITION; POSITION; SPRAY; NOSE;
D O I
10.1002/alr.21894
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background: Improvement in topical delivery to nasal mucosa is a fundamental goal of endoscopic sinus surgery (ESS). This study compares the penetration of irrigation before and after middle turbinate resection (MTR) to assess the efficacy of topical delivery. Methods: ESS was performed on 4 cadaver heads, followed by MTR. Each head was irrigated with fluorescein-dyed water using a squeeze bottle both before and after MTR. Videos were recorded by rigid nasal endoscopy. Four blinded raters reviewed videos and scored the extent of staining (0 to 3) for each site. Results: The mean score for the extent of staining of all anatomical sites before and after MTR was 1.30 and 1.92, respectively (p = 0.035). The mean score for extent of staining before and after MTR was 2.56 and 2.81 (p = 0.134) for the maxillary sinus, 1.66 and 2.25 (p = 0.022) for the ethmoid sinus, 1.03 and 1.94 (p = 0.263) for the sphenoid sinus, 0.16 and 0.94 (p = 0.055) for the frontal sinus, and 1.09 and 1.66 (p = 0.340) for the olfactory cleft, respectively. When evaluating interrater reliability, Cronbach's alpha was 0.92, which is acceptable. When evaluating intrarater reliability, the Fleiss kappa statistic for each rater was excellent or good. Conclusion: Overall, MTR results in significant improvement in the penetration of nasal irrigations in the cadaver model. Each individual sinus displays a trend toward improvement; however, only the ethmoid sinus displays a statistically significant improvement. Further in vivo studies are needed to elucidate the role of MTR. (C) 2016 ARS-AAOA, LLC.
引用
收藏
页码:338 / 342
页数:5
相关论文
共 27 条
  • [1] Irrigation penetration of nasal delivery systems: A cadaver study
    Abadie, Wesley M.
    McMains, Kevin C.
    Weitzel, Erik Kent
    [J]. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2011, 1 (01) : 46 - 49
  • [2] Frontal sinus surgery and sinus distribution of nasal irrigation
    Barham, Henry P.
    Ramakrishnan, Vijay R.
    Knisely, Anna
    Timothy Quy-Phong Do
    Chan, Lyndon S.
    Gunaratne, Dakshika A.
    Weston, Jared D.
    Seneviratne, Sheran
    Marcells, George N.
    Sacks, Raymond
    Harvey, Richard J.
    [J]. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2016, 6 (03) : 238 - 242
  • [3] Ambulatory Sinus and Nasal Surgery in the United States: Demographics and Perioperative Outcomes
    Bhattacharyya, Neil
    [J]. LARYNGOSCOPE, 2010, 120 (03) : 635 - 638
  • [4] Unexpected consequences of transnasal balloon dilation of the maxillary ostium
    Brenner, Pryor S.
    Abadie, Wesley M.
    Weitzel, Erik K.
    Thomas, Roy F.
    McMains, Kevin C.
    [J]. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2011, 1 (06) : 466 - 470
  • [5] Comparison of delivery of topical medications to the paranasal sinuses via "vertex-to-floor" position and atomizer spray after FESS
    Cannady, SB
    Batra, PS
    Citardi, MJ
    Lanza, DC
    [J]. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2005, 133 (05) : 735 - 740
  • [6] WHAT IS COEFFICIENT ALPHA - AN EXAMINATION OF THEORY AND APPLICATIONS
    CORTINA, JM
    [J]. JOURNAL OF APPLIED PSYCHOLOGY, 1993, 78 (01) : 98 - 104
  • [7] Cronbach LJ, 1951, PSYCHOMETRIKA, V16, P297
  • [8] The effect of inferior turbinate hypertrophy on nasal spray distribution to the middle meatus
    Dowley, AC
    Homer, JJ
    [J]. CLINICAL OTOLARYNGOLOGY, 2001, 26 (06): : 488 - 490
  • [9] Empty Nose Syndrome: Limbic System Activation Observed by Functional Magnetic Resonance Imaging
    Freund, Wolfgang
    Wunderlich, Arthur P.
    Stoecker, Tony
    Schmitz, Bernd L.
    Scheithauer, Marc O.
    [J]. LARYNGOSCOPE, 2011, 121 (09) : 2019 - 2025
  • [10] Pre- and Postoperative Sinus Penetration of Nasal Irrigation
    Grobler, Alethea
    Weitzel, Erik K.
    Buele, Achim
    Jardeleza, Camille
    Cheong, Yew C.
    Field, John
    Wormald, Peter-John
    [J]. LARYNGOSCOPE, 2008, 118 (11) : 2078 - 2081