Stereoselective synthesis of (2S, 8S)-2-benzyl hexahydro-pyrrodizin-3-one starting from (L)-proline based on stereoselective benzylation

被引：4

作者：

Jin, JY ^{[1
]}

Zheng, MH ^{[1
]}

Wu, X ^{[1
]}

Tian, GR ^{[1
]}

机构：

[1] Yan Bian Univ, Dept Chem, Yan Ji City 133002, Ji Lin, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2004年 / 34卷 / 17期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1081/SCC-200028616

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A pyrrolizidine alkaloid, (2S, 8S)-2-benzyl hexahydro-pyrrodizin-3-one, was synthesized from (L)-proline using diastereoselective benzylation as the key step. The absolute configuration of the target compound was confirmed through 2D H-H COSY and H-H NOESY spectra.

引用

页码：3191 / 3196

页数：6

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