A Case of HLA-DRB1-MET Rearranged Lung Adenocarcinoma With Rapid Response to Crizotinib

被引：8

作者：

Kunte, Siddharth ^{[1
]}

Stevenson, James ^{[1
]}

机构：

[1] Cleveland Clin, Taussig Canc Inst, Cleveland, OH 44106 USA

来源：

CLINICAL LUNG CANCER | 2021年 / 22卷 / 03期

关键词：

Crizotinib; HLA-DRB1-MET rearrangement; MET fusions; Non-small-cell lung cancer; Targeted treatments; CANCER;

D O I：

10.1016/j.cllc.2020.05.005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

MET gene rearrangements are rare but actionable alterations found in lung adenocarcinomas. Next-generation sequencing can help identify MET rearrangements. Crizotinib has shown excellent responses for MET rearranged lung adenocarcinomas in case reports. (C) 2020 Elsevier Inc. All rights reserved.

引用

页码：E298 / E300

页数：3

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