Emergence of a novel macrolide-resistant Streptococcus pyogenes emm53 strain

被引：4
作者：
Strakova, L.
Motlova, J.
Jakubu, V.
Urbaskova, P.
Kriz, P.
机构：
[1] NIPH, Natl Reference Lab Streptococci & Enterococci, Prague 10042 10, Czech Republic
[2] NIPH, WHO Collaborating Ctr Reference & Res Streptococc, Prague 10042 10, Czech Republic
[3] NIPH, NRL Antibiot, Prague 10042 10, Czech Republic
来源：
CLINICAL MICROBIOLOGY AND INFECTION | 2007年 / 13卷 / 04期
关键词：
antibiotic resistance; emm type; group A streptococcus; multilocus sequence typing; pulsed-field gel electrophoresis; Streptococcus pyogenes;
D O I：
10.1111/j.1469-0691.2006.01658.x
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
An unusual emm53, T-28/T-non-typeable, iMLS(B) phenotype clone represented a substantial proportion (28.6%) of invasive erythromycin-resistant group A streptococcus (GAS) isolates in the Czech Republic during 2003. Clonal analysis of emm53 isolates between 2001 and 2004 revealed four pulsed-field gel electrophoresis (PFGE) patterns and two emm subtypes. Isolates produced identical PFGE patterns regardless of their invasiveness and/or tetracycline resistance. Multilocus sequence typing classified all isolates as ST340. An ST5 (emm83) isolate, a potential ancestor of ST340, was isolated in the Czech Republic from an impetigo patient in 1988. The Czech emm53/ST340 isolates shared only three of seven alleles with the original Lancefield emm53/ST11 isolate.
引用
收藏
页码：443 / 445
页数：3
相关论文
共 14 条
[1]   Rapid pulsed-field gel electrophoresis method for group B streptococcus isolates [J].
Benson, JA ;
Ferrieri, P .
JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (08) :3006-3008
[2]   Emergence of macrolide-resistant Streptococcus pyogenes strains in French children [J].
Bingen, E ;
Bidet, P ;
Mihaila-Amrouche, L ;
Doit, C ;
Forcet, S ;
Brahimi, N ;
Bouvet, A ;
Cohen, R .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (09) :3559-3562
[3]  
CLSI-Clinical Laboratory Standard Institute, 2005, M100S15 CLSI
[4]   Resistance to erythromycin and telithromycin in Streptococcus pyogenes isolates obtained between 1999 and 2002 from Greek children with tonsillopharyngitis:: Phenotypic and genotypic analysis [J].
Grivea, IN ;
Al-Lahham, A ;
Katopodis, GD ;
Syrogiannopoulos, GA ;
Reinert, RR .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (01) :256-261
[5]  
Jasir A., 2005, EUROSURVEILLANCE, V10
[6]  
Johnson DR., 1996, LAB DIAGNOSIS GROUP
[7]   3 DIFFERENT PHENOTYPES OF ERYTHROMYCIN-RESISTANT STREPTOCOCCUS-PYOGENES IN FINLAND [J].
SEPPALA, H ;
NISSINEN, A ;
YU, Q ;
HUOVINEN, P .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1993, 32 (06) :885-891
[8]  
SILJANDER T, 2005, CLIN MICROBIOL INFEC, V11, P567
[9]   Rapid inversion of the prevalences of macrolide resistance phenotypes paralleled by a diversification of T and emm types among Streptococcus pyogenes in Portugal [J].
Silva-Costa, C ;
Ramirez, A ;
Meto-Cristino, J .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (05) :2109-2111
[10]  
Strakovi L., 2004, Epidemiologie Mikrobiologie Imunologie, V53, P106
12