机构:
Univ Maine, St Joseph Hosp, Maine Ctr Osteoporosis Res & Educ, Bangor, ME 04401 USAUniv Maine, St Joseph Hosp, Maine Ctr Osteoporosis Res & Educ, Bangor, ME 04401 USA
Rosen, CJ
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机构:
[1] Univ Maine, St Joseph Hosp, Maine Ctr Osteoporosis Res & Educ, Bangor, ME 04401 USA
This article discusses the clinical use of insulin-like growth factors (IGF) as a potential diagnostic tool for osteoporosis. Although there is a numerical relationship between measurable IGF-I and bone mass, or risk of fractures, it is not clear that it is causal. Caution must be undertaken in deciphering the results of a low, normal, or high IGF-I in relation to osteoporosis. Further studies should help define more clearly the possible pathogenic relationship between IGF-I and bone mass.