Poly Cystic Ovarian Syndrome: An Updated Overview

被引:165
作者
El Hayek, Samer [1 ]
Bitar, Lynn [1 ]
Hamdar, Layal H. [1 ]
Mirza, Fadi G. [2 ,3 ]
Daoud, Georges [1 ]
机构
[1] Amer Univ Beirut, Fac Med, Dept Anat Cell Biol & Physiol Sci, Beirut, Lebanon
[2] Amer Univ Beirut, Fac Med, Dept Obstet & Gynecol, Beirut, Lebanon
[3] Columbia Univ Coll Phys & Surg, Dept Obstet & Gynecol, New York, NY 10032 USA
关键词
PCOS; ovary; insulin; obesity; diabetes; IMPAIRED GLUCOSE-TOLERANCE; QUALITY-OF-LIFE; INSULIN SENSITIZER PIOGLITAZONE; REGULAR MENSTRUAL CYCLES; OMENTAL ADIPOSE-TISSUE; IN-VITRO FERTILIZATION; D-CHIRO-INOSITOL; POLYCYSTIC-OVARY; SYNDROME PCOS; METABOLIC SYNDROME;
D O I
10.3389/fphys.2016.00124
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Poly Cystic Ovarian Syndrome (PCOS) is one of the most common metabolic and reproductive disorders among women of reproductive age. Women suffering from PCOS present with a constellation of symptoms associated with menstrual dysfunction and androgen excess, which significantly impacts their quality of life. They may be at increased risk of multiple morbidities, including obesity, insulin resistance, type II diabetes mellitus, cardiovascular disease (CVD), infertility, cancer, and psychological disorders. This review summarizes what the literature has so far provided from guidelines to diagnosis of PCOS. It will also present a general overview about the morbidities associated with this disease, specifically with its more severe classic form. Finally, the review will stress on the various aspects of treatment and screening recommendations currently used in the management of this condition.
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页数:15
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