Limited Dissemination of Extended-Spectrum β-Lactamase- and Plasmid-Encoded AmpC-Producing Escherichia coli from Food and Farm Animals, Sweden

被引：60

作者：

Borjesson, Stefan ^{[1
]}

Ny, Sofia ^{[2
]}

Egervarn, Maria ^{[3
]}

Bergstrom, Jakob ^{[2
]}

Rosengren, Asa ^{[3
]}

Englund, Stina ^{[1
]}

Lofmark, Sonja ^{[2
]}

Byfors, Sara ^{[2
]}

机构：

[1] Natl Vet Inst, S-75007 Uppsala, Sweden

[2] Publ Hlth Agcy Sweden, Stockholm, Sweden

[3] Natl Food Agcy, Uppsala, Sweden

来源：

EMERGING INFECTIOUS DISEASES | 2016年 / 22卷 / 04期

关键词：

SWEDISH BROILERS; CHICKEN MEAT; RISK-FACTORS; RESISTANCE; COLONIZATION; BLA(CTX-M-1); SPREAD; FRANCE; TRAVEL; GENES;

D O I：

10.3201/eid2204.151142

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Extended-spectrum beta-lactamase (ESBL)- and plasmid-encoded ampC (pAmpC)-producing Enterobacteriaceae might spread from farm animals to humans through food. However, most studies have been limited in number of isolates tested and areas studied. We examined genetic relatedness of 716 isolates from 4,854 samples collected from humans, farm animals, and foods in Sweden to determine whether foods and farm animals might act as reservoirs and dissemination routes for ESBL/pAmpC-producing Escherichia coli. Results showed that clonal spread to humans appears unlikely. However, we found limited dissemination of genes encoding ESBL/pAmpC and plasmids carrying these genes from foods and farm animals to healthy humans and patients. Poultry and chicken meat might be a reservoir and dissemination route to humans. Although we found no evidence of clonal spread of ESBL/pAmpC-producing E. coli from farm animals or foods to humans, ESBL/pAmpC-producing E. coli with identical genes and plasmids were present in farm animal, foods, and humans.

引用

页码：634 / 640

页数：7

共 23 条

[1]

[Anonymous], 2011, EFSA J

[2]

[Anonymous], 2007, The world health report

[3] Characterization of plasmid-mediated AmpC-producing E.coli from Swedish broilers and association with human clinical isolates [J].