Rh-catalyzed sequential hydroarylation/hydrovinylation-heterocyclization of β-(2-aminophenyl)-α,β-ynones with organoboron derivatives:: A new approach to functionalized quinolines

被引：48

作者：

Abbiati, Giorgio

Arcadi, Antonio

Marinelli, Fabio

Rossi, Ellsabetta

Verdecchia, Mirella

机构：

[1] Univ Milan, Ist Chim Organ Alessandro Marchesini, I-20133 Milan, Italy

[2] Univ Aquila, Dipartimento Chim Ingn Chim & Mat, I-67010 Coppito, Italy

来源：

SYNLETT | 2006年 / 19期

关键词：

quinolines; hydroarylation; rhodium; alkynones; arylboronic acids;

D O I：

10.1055/s-2006-956462

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-Aryl and 4-vinyl quinolines were prepared via a sequential procedure involving regioselective Rh(acae)(C2H2)/dppf-catalyzed hydroarylation/hydrovinylation of beta-(2-aminophenyl)-alpha,beta-ynones with arylboronic acids or potassium aryl and vinyl trifluoroborates, followed by nucleophilic attack of the amino group onto the carbonyl.

引用

页码：3218 / 3224

页数：7

共 49 条

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