Rh-catalyzed sequential hydroarylation/hydrovinylation-heterocyclization of β-(2-aminophenyl)-α,β-ynones with organoboron derivatives:: A new approach to functionalized quinolines

被引：48
作者：
Abbiati, Giorgio
Arcadi, Antonio
Marinelli, Fabio
Rossi, Ellsabetta
Verdecchia, Mirella
机构：
[1] Univ Milan, Ist Chim Organ Alessandro Marchesini, I-20133 Milan, Italy
[2] Univ Aquila, Dipartimento Chim Ingn Chim & Mat, I-67010 Coppito, Italy
来源：
SYNLETT | 2006年 / 19期
关键词：
quinolines; hydroarylation; rhodium; alkynones; arylboronic acids;
D O I：
10.1055/s-2006-956462
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
4-Aryl and 4-vinyl quinolines were prepared via a sequential procedure involving regioselective Rh(acae)(C2H2)/dppf-catalyzed hydroarylation/hydrovinylation of beta-(2-aminophenyl)-alpha,beta-ynones with arylboronic acids or potassium aryl and vinyl trifluoroborates, followed by nucleophilic attack of the amino group onto the carbonyl.
引用
收藏
页码：3218 / 3224
页数：7
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