Exposure to alcohol and overall survival in head and neck cancer: A regional cohort study

被引：23

作者：

Denissoff, Alexander ^{[1
,2
]}

Huusko, Teemu ^{[3
,4
]}

Ventela, Sami ^{[3
,4
]}

Niemela, Solja ^{[1
,2
]}

Routila, Johannes ^{[3
,4
]}

机构：

[1] Univ Turku, Fac Med, Dept Psychiat, Turku, Finland

[2] Turku Univ Hosp, Dept Psychiat, Addict Psychiat Unit, Turku, Finland

[3] Univ Turku, Dept Otorhinolaryngol Head & Neck Surg, Turku, Finland

[4] Turku Univ Hosp, Dept Otorhinolaryngol Head & Neck Surg, Kiinamyllynkatu 4-8, FI-20521 Turku, Finland

来源：

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2022年 / 44卷 / 10期

关键词：

alcohol; history; HNSCC; survival; tobacco; POOLED ANALYSIS; PRIMARY-CARE; INTERNATIONAL HEAD; CONSUMPTION; SMOKING; INTERVENTION; DRINKERS; RISK; EFFICACY; TOBACCO;

D O I：

10.1002/hed.27125

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Background There is a paucity of knowledge regarding the association of alcohol use with overall survival (OS) of patients with head and neck squamous cell carcinoma (HNSCC). Methods All 1033 patients treated for new HNSCC in Southwest Finland regional referral center of Turku University Hospital in 2005-2015. Cox regression analysis was used. Tumor TNM classification, age at baseline and tobacco smoking status were assessed as potential confounders. Results A history of severe harmful alcohol use with major somatic complications (HR: 1.41; 95%CI: 1.06-1.87; p = 0.017) as well as current use of at least 10 units per week (HR: 1.44, 95%CI: 1.16-1.78; p = 0.001) were associated with OS. Conclusions Alcohol consumption of 10-20 units/week, often regarded as moderate use, was found to increase risk of mortality independent of other prognostic variables. Systematic screening of risk level alcohol use and prognostic evaluation of alcohol brief intervention strategies is highly recommended.

引用

页码：2109 / 2117

页数：9

共 37 条

[1] Predictors of Survival After Head and Neck Squamous Cell Carcinoma in South America: The InterCHANGE Study [J].

Abrahao, Renata ;

Perdomo, Sandra ;

Ribeiro Pinto, Luis Felipe ;

de Carvalho, Flavia Nascimento ;

Dias, Fernando Luis ;

de Podesta, Jose Roberto V. ;

von Zeidler, Sandra Ventorin ;

de Abreu, Priscila Marinho ;

Vilensky, Marta ;

Eduardo Giglio, Raul ;

Oliveira, Jose Carlos ;

Mineiro, Matinair Siqueira ;

Kowalski, Luiz P. ;

Ikeda, Mauro K. ;

Cuello, Mauricio ;

Munyo, Andres ;

Rodriguez-Urrego, Paula A. ;

Antonio Hakim, Jose ;

Alfonso Suarez-Zamora, David ;

Cayol, Federico ;

Fernando Figari, Marcelo ;

Oliver, Javier ;

Gaborieau, Valerie ;

Keogh, Ruth H. ;

Brennan, Paul ;

Curado, Maria Paula .

JCO GLOBAL ONCOLOGY, 2020, 6 :486-499

[2] The influence of smoking, age and stage at diagnosis on the survival after larynx, hypopharynx and oral cavity cancers in Europe: The ARCAGE study [J].

Abrahao, Renata ;

Anantharaman, Devasena ;

Gaborieau, Valerie ;

Abedi-Ardekani, Behnoush ;

Lagiou, Pagona ;

Lagiou, Areti ;

Ahrens, Wolfgang ;

Holcatova, Ivana ;

Betka, Jaroslav ;

Merletti, Franco ;

Richiardi, Lorenzo ;

Kjaerheim, Kristina ;

Serraino, Diego ;

Polesel, Jerry ;

Simonato, Lorenzo ;

Alemany, Laia ;

Agudo Trigueros, Antonio ;

Macfarlane, Tatiana V. ;

Macfarlane, Gary J. ;

Znaor, Ariana ;

Robinson, Max ;

Canova, Cristina ;

Conway, David I. ;

Wright, Sylvia ;

Healy, Claire M. ;

Toner, Mary ;

Cadoni, Gabriella ;

Boccia, Stefania ;

Gheit, Tarik ;

Tommasino, Massimo ;

Scelo, Ghislaine ;

Brennan, Paul .

INTERNATIONAL JOURNAL OF CANCER, 2018, 143 (01) :32-44

[3] Cancer Survivors' Uptake and Adherence in Diet and Exercise Intervention Trials: An Integrative Data Analysis [J].

Adams, Rebecca N. ;

Mosher, Catherine E. ;

Blair, Cindy K. ;

Snyder, Denise C. ;

Sloane, Richard ;

Demark-Wahnefried, Wendy .

CANCER, 2015, 121 (01) :77-83

[4] Alcohol consumption and site-specific cancer risk: a comprehensive dose-response meta-analysis [J].

Bagnardi, V. ;

Rota, M. ;

Botteri, E. ;

Tramacere, I. ;

Islami, F. ;

Fedirko, V. ;

Scotti, L. ;

Jenab, M. ;

Turati, F. ;

Pasquali, E. ;

Pelucchi, C. ;

Galeone, C. ;

Bellocco, R. ;

Negri, E. ;

Corrao, G. ;

Boffetta, P. ;

La Vecchia, C. .

BRITISH JOURNAL OF CANCER, 2015, 112 (03) :580-593

[5] Efficacy of brief interventions for hazardous drinkers in primary care:: Systematic review and meta-analyses [J].

Ballesteros, J ;

Duffy, JC ;

Querejeta, I ;

Ariño, J ;

González-Pinto, A .

ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH, 2004, 28 (04) :608-618

[6] Tobacco smoking and alcohol drinking at diagnosis of head and neck cancer and all-cause mortality: Results from head and neck 5000, a prospective observational cohort of people with head and neck cancer [J].

Beynon, Rhona A. ;

Lang, Samantha ;

Schimansky, Sarah ;

Penfold, Christopher M. ;

Waylen, Andrea ;

Thomas, Steven J. ;

Pawlita, Michael ;

Waterboer, Tim ;

Martin, Richard M. ;

May, Margaret ;

Ness, Andy R. .

INTERNATIONAL JOURNAL OF CANCER, 2018, 143 (05) :1114-1127

[7] Drinking pattern is more strongly associated with under-reporting of alcohol consumption than socio-demographic factors: evidence from a mixed-methods study [J].

Boniface, Sadie ;

Kneale, James ;

Shelton, Nicola .

BMC PUBLIC HEALTH, 2014, 14

[8] A tailored smoking, alcohol, and depression intervention for head and neck cancer patients [J].

Duffy, Sonia A. ;

Ronis, David L. ;

Valenstein, Marcia ;

Lambert, Michael T. ;

Fowler, Karen E. ;

Gregory, Lynn ;

Bishop, Carol ;

Myers, Larry L. ;

Blow, Frederic C. ;

Terrell, Jeffrey E. .

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2006, 15 (11) :2203-2208

[9] Pretreatment Health Behaviors Predict Survival Among Patients With Head and Neck Squamous Cell Carcinoma [J].

Duffy, Sonia A. ;

Ronis, David L. ;

McLean, Scott ;

Fowler, Karen E. ;

Gruber, Stephen B. ;

Wolf, Gregory T. ;

Terrell, Jeffrey E. .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (12) :1969-1975

[10] INFLUENCE OF SMOKING AND ALCOHOL DRINKING BEHAVIORS ON TREATMENT OUTCOMES OF PATIENTS WITH SQUAMOUS CELL CARCINOMAS OF THE HEAD AND NECK [J].

Fortin, Andre ;

Wang, Chang Shu ;

Vigneault, Eric .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 74 (04) :1062-1069

← 1 2 3 4 →