Translocation t(1;10)(q21;q26) in a case of acute nonlymphocytic leukemia

被引：2

作者：

Terreros, MC

Quesada, M

Slavutsky, IR

机构：

[1] Hosp Neuropsiquiatr Especializado Dr Alejandro Kor, Area Citogenet, Serv Anat Patol, La Plata, Argentina

[2] Acad Nacl Med, Inst Invest Hematol Mariano R Castex, Dept Genet, Buenos Aires, DF, Argentina

来源：

ACTA HAEMATOLOGICA | 1998年 / 99卷 / 02期

关键词：

acute nonlymphocytic leukemia; chromosome abnormalities; hematologic malignancies; t(1; 10);

D O I：

10.1159/000040818

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Chromosome banding studies carried out on bone marrow cells from a 16 year-old boy with an M1 acute nonlymphocytic leukemia (ANLL) revealed an unbalanced translocation involving chromosomes 1 and 10: der(10) t(1;10) (q21;q26) that results in a partial trisomy 1q between bands 1q21-1qter. Marker del(6)(q21) and trisomies of chromosomes 18, 21 and 22 were also observed. To our knowledge, this der(10) is the first to be reported in a patient with ANLL.

引用

页码：92 / 94

页数：3