Electrohydrodynamic stretching of DNA in confined environments

被引：206

作者：

Bakajin, OB ^{[1
]}

Duke, TAJ

Chou, CF

Chan, SS

Austin, RH

Cox, EC

机构：

[1] Princeton Univ, Dept Phys, Princeton, NJ 08544 USA

[2] Univ Cambridge, Cavendish Lab, Cambridge CB3 0HE, England

[3] Princeton Univ, Dept Biol Mol, Princeton, NJ 08544 USA

来源：

PHYSICAL REVIEW LETTERS | 1998年 / 80卷 / 12期

关键词：

D O I：

10.1103/PhysRevLett.80.2737

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

The effect of confinement on the dynamics of polymers was studied by observing the transient extension and relaxation of single DNA molecules as they interacted with obstacles in a specially designed thin slit. Viscous drag was found to increase with the degree of confinement, which we interpret in terms of hydrodynamic screening by the planar surfaces of the slit. Since the DNA was driven by an electrophoretic force, the experimental data support the notion that an electric field acts on a tethered polyelectrolyte equivalently to a hydrodynamic flow.

引用

页码：2737 / 2740

页数：4

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