Perspective on Ruthenium-Copper-Mediated Dehydrogenative C-N Bond Formation

被引：23

作者：

Biafora, Agostino ^{[1
]}

Patureau, Frederic W. ^{[1
]}

机构：

[1] Kaiserslautern Univ Technol, Dept Chem, Kaiserslautern, Germany

来源：

SYNLETT | 2014年 / 25卷 / 18期

关键词：

C-H activation; oxidative amination; dehydrogenative cross-coupling; axial chirality; lauternamines; H BONDS; REDUCTIVE ELIMINATION; CARBON-CARBON; CARBAZOLE; AMINATION; FUNCTIONALIZATION; DERIVATIVES; AMIDATION;

D O I：

10.1055/s-0034-1378999

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In 2014, the direct dehydrogenative construction of ubiquitous C-N bonds remains a significant challenge, but recent communications in this field show that this is about to change. Here we highlight a novel ruthenium-catalyzed method for C-H activation and dehydrogenative C-N cross-coupling of unprotected diarylamines in an intermolecular fashion, with carbazoles. The resulting compounds, lauternamines, show unexpected and unprecedented H-bonded stabilized axial chirality. These promise new exciting developments in C-N dehydrogenative couplings.

引用

页码：2525 / 2530

页数：6

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