Synthesis and biological activity of some new 1,3-thiazolyl-6-bromoquinazolin-4(3H)ones

被引:0
作者
Patel, N. B. [1 ]
Patel, J. N. [1 ]
机构
[1] Veer Narmad S Gujarat Univ, Dept Chem, Surat 395007, Gujarat, India
关键词
Quinazolin-4(3H)one; 1,3-thiazole; antibacterial; antifungal; ANTIBACTERIAL ACTIVITY; DERIVATIVES; AGENTS; ACID; (3H)-ONES; AMIDES;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The title compound 1,3-thiazolyl-6-bromoquinazolin-4(3H)ones 5(l-XV) have been synthesized from the molecule 2-[(2,6-dichlorophenyl)amino]phenyl acetic acid 1 through multi-step reaction sequence. The structures of new compounds have been confirmed by elemental analyses, IR, H-1 and C-13 NMR spectral data. All the compounds were evaluated for their in vitro antibacterial and antifungal activities.
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页码:1231 / 1236
页数:6
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