Lymphoproliferative disease and acquired C1 inhibitor deficiency

被引：69

作者：

Castelli, Roberto

Deliliers, Daniela Lambertenghi

Zingale, Lorenza C.

Pogliani, Enrico Maria

Cicardi, Marco

机构：

[1] Osped Maggiore, Politecn Milan, IRCCS Fdn, Dept Internal Med & Med Special,Div Internal Med, I-20122 Milan, Italy

[2] Univ Milan, Bicocca Osped San Gerardo Monza, Sacco Hosp, Div Internal Med 2,Clin Ematol, Milan, Italy

来源：

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL | 2007年 / 92卷 / 05期

关键词：

C1; inhibitor; deficiency; acquired; lymphoproliferative; autoantibody;

D O I：

10.3324/haematol.10769

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Angioedema due to acquired deficiency of the CI-inhibitor is a bridging condition between autoimmunity and lymphoproliferation. We report 32 patients with acquired CI inhibitor deficiency: 23 have anti CI-inhibitor autoantibodies; 13 have monoclonal gammopathies of unknown significance and 9 have non-Hodgkin's lymphoma. Our series suggest that different forms of B cell disorders coexist and/or evolve into each other in acquired angioedema.

引用

页码：716 / 718

页数：3

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