An easily reproducible, hand-held, single-sided, MRI sensor

被引:17
作者
Greer, Mason [1 ]
Chen, Cheng [1 ]
Mandal, Soumyajit [1 ]
机构
[1] Case Western Reserve Univ, 10900 Euclid Ave, Cleveland, OH 44106 USA
基金
美国国家科学基金会;
关键词
Single-sided NMR; NMR-MOUSE; Portable MRI; NMR-MOUSE; EXCITATION; DIFFUSION; SEQUENCES;
D O I
10.1016/j.jmr.2019.106591
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Single-sided MRI sensors allow the imaging of samples that are larger than the magnet. Thus, they enable truly portable imagers with potential applications in medicine, quality assurance (QA), agriculture, material science, and other fields. However, despite recent advancements, single-sided MRI systems are relatively uncommon. This is partially due to the limited number of commercial products. Also, current implementations often require large and/or complex magnet arrays which require machining techniques such as milling or drilling. These techniques must be performed to tight tolerances to ensure accuracy of the B0 field. Furthermore, these systems generally have hand-wound RF or gradient coils that are not trivial to construct. The main goals of this work are to reduce the size of single-sided MRI sensors while simultaneously making them more accessible for others to build. To this end, we present a hand-held, single-sided, MRI sensor that is constructed using an easy-to-assemble magnet array, a 3D-printed housing, and printed circuit boards (PCBs) that contain the RF coil, gradient coils, and matching network. By implementing all coils directly on PCBs, the geometry can be easily optimized and then manufactured at low cost. Both spin density-weighted and T-1-weighted images of various samples are presented to demonstrate the capabilities of the proposed sensor. (C) 2019 Elsevier Inc. All rights reserved.
引用
收藏
页数:18
相关论文
共 35 条
[1]   Construction of a NMR-MOUSE with short dead time [J].
Anferova, S ;
Anferov, V ;
Adams, M ;
Blümler, P ;
Routley, N ;
Hailu, K ;
Kupferschläger, K ;
Mallett, MJD ;
Schroeder, G ;
Sharma, S ;
Blümich, B .
CONCEPTS IN MAGNETIC RESONANCE, 2002, 15 (01) :15-25
[2]   Design and experimental validation of Unilateral Linear Halbach magnet arrays for single-sided magnetic resonance [J].
Bashyam, Ashvin ;
Li, Matthew ;
Cima, Michael J. .
JOURNAL OF MAGNETIC RESONANCE, 2018, 292 :36-43
[3]   The NMR-mouse:: Construction, excitation, and applications [J].
Blümich, B ;
Blümler, P ;
Eidmann, G ;
Guthausen, A ;
Haken, R ;
Schmitz, U ;
Saito, K ;
Zimmer, G .
MAGNETIC RESONANCE IMAGING, 1998, 16 (5-6) :479-484
[4]  
Brown RW., 2014, Magnetic Resonance Imaging: Physical Principles and Sequence Design
[5]  
Callaghan T. Paul, 1993, PRINCIPLES NUCL MAGN
[6]   Two-dimensional imaging with a single-sided NMR probe [J].
Casanova, F ;
Blümich, B .
JOURNAL OF MAGNETIC RESONANCE, 2003, 163 (01) :38-45
[7]   Self-diffusion coefficient by single-sided NMR [J].
Casieri, C ;
Bubici, S ;
De Luca, F .
JOURNAL OF MAGNETIC RESONANCE, 2003, 162 (02) :348-355
[8]   Recent advances in emerging imaging techniques for non-destructive detection of food quality and safety [J].
Chen, Quansheng ;
Zhang, Chaojie ;
Zhao, Jiewen ;
Ouyang, Qin .
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2013, 52 :261-274
[9]   Quantitative magnetic resonance imaging of 'Fuyu' persimmon fruit during development and ripening [J].
Clark, CJ ;
MacFall, JS .
MAGNETIC RESONANCE IMAGING, 2003, 21 (06) :679-685
[10]   Fluid assessment in dialysis patients by point-of-care magnetic relaxometry [J].
Colucci, Lina A. ;
Corapi, Kristin M. ;
Li, Matthew ;
Parada, Xavier Vela ;
Allegretti, Andrew S. ;
Lin, Herbert Y. ;
Ausiello, Dennis A. ;
Rosen, Matthew S. ;
Cima, Michael J. .
SCIENCE TRANSLATIONAL MEDICINE, 2019, 11 (502)