Poor prognosis in cycles following "genuine" empty follicle syndrome

被引:8
作者
Coskun, Serdar [1 ,2 ]
Madan, Samira [3 ,4 ]
Bukhari, Ibtihal [3 ,4 ]
Al-Hassan, Saad [3 ,4 ]
Al-Rejjal, Rafat [3 ,4 ]
Awartani, Khalid [3 ,4 ]
机构
[1] King Faisal Specialist Hosp & Res Ctr, Dept Pathol, Riyadh 11211, Saudi Arabia
[2] King Faisal Specialist Hosp & Res Ctr, Dept Lab Med, Riyadh 11211, Saudi Arabia
[3] King Faisal Specialist Hosp & Res Ctr, Dept Obstet, Riyadh 11211, Saudi Arabia
[4] King Faisal Specialist Hosp & Res Ctr, Dept Gynecol, Riyadh 11211, Saudi Arabia
关键词
Empty follicle syndrome; IVF; Pregnancy; Prognosis; OOCYTE RETRIEVAL; PATIENT;
D O I
10.1016/j.ejogrb.2010.02.013
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objectives: The aim of this study was to investigate the prognosis in future IVF cycles of patients with empty follicle syndrome (EFS). Study design: EFS cases and their future cycles were reviewed. Clinical pregnancy rate per started cycle was taken as the primary outcome in assessing the future outcome in IVF treatment cycles. Results: A total of 3023 patients underwent 5238 IVF treatment cycles. Twenty-six patients (1%) had a total of 58 (1%) cycles of EFS. Thirteen women went through 32 further IVF treatment cycles following the diagnosis of EFS, yielding only two clinical pregnancies, giving a clinical pregnancy rate of 6.25% per started cycle. In addition, four patients had recurrence in a total of 15 cycles. Conclusions: The occurrence of EFS will indicate poor IVF success in subsequent IVF cycles. Patients with "genuine EFS" should be counselled about the outcome of their future IVF cycles. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:157 / 159
页数:3
相关论文
共 20 条
[1]  
ASHKENAZI J, 1987, FERTIL STERIL, V48, P152
[2]  
BENSHLOMO I, 1991, FERTIL STERIL, V55, P324
[3]   Unsuccessful oocyte retrieval: technical artefact or genuine 'empty follicle syndrome'? [J].
Bustillo, M .
REPRODUCTIVE BIOMEDICINE ONLINE, 2004, 8 (01) :59-67
[4]   Day 5 versus day 3 embryo transfer: a controlled randomized trial [J].
Coskun, S ;
Hollanders, J ;
Al-Hassan, S ;
Al-Sufyan, H ;
Al-Mayman, H ;
Jaroudi, K .
HUMAN REPRODUCTION, 2000, 15 (09) :1947-1952
[5]  
COULAM CB, 1986, FERTIL STERIL, V46, P1153
[6]   Evidence of 'genuine empty follicles' in follicular aspirate: a case report† [J].
Desai, N. ;
Austin, C. ;
AbdelHafez, F. ;
Goldfarb, J. ;
Falcone, T. .
HUMAN REPRODUCTION, 2009, 24 (05) :1171-1175
[7]  
Inan MS, 2006, REPROD BIOMED ONLINE, V13, P481
[8]  
Khalaf Y, 1997, HUM REPROD, V12, P1601
[9]   RECURRENT EMPTY FOLLICLE SYNDROME [J].
LASALA, GB ;
GHIRARDINI, G ;
CANTARELLI, M ;
DOTTI, C ;
CAVALIERI, S ;
TORELLI, MG .
HUMAN REPRODUCTION, 1991, 6 (05) :651-652
[10]   Successful treatment of empty follicle syndrome by triggering endogenous LH surge using GnRH agonist in an antagonist down-regulated IVF cycle [J].
Lok, F ;
Pritchard, J ;
Lashen, H .
HUMAN REPRODUCTION, 2003, 18 (10) :2079-2081