Mitochondrial dysfunction and oxidative stress in CHF

被引:77
作者
Okonko, Darlington O. [1 ]
Shah, Ajay M. [1 ]
机构
[1] Kings Coll London, British Heart Fdn Ctr Excellence, Div Cardiovasc, London SE5 9NU, England
关键词
HEART-FAILURE;
D O I
10.1038/nrcardio.2014.189
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The results of the Q-SYMBIO trial showing a reduction in mortality in patients with heart failure treated with coenzyme Q(10) have substantial limitations. Nevertheless, they highlight the need to identify effective new therapies targeted at mitochondrial dysfunction and oxidative stress in heart failure.
引用
收藏
页码:6 / 7
页数:2
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