Antimicrobial Activity Investigation on Wuyiencin Fractions of Different Polarity

被引：5

作者：

Cui, Zengjie ^{[1
]}

Zhang, Kecheng ^{[1
]}

She, Gaimei ^{[2
]}

Lin, Yinni ^{[3
]}

Sun, Lei ^{[1
]}

Cheng, Yan ^{[1
]}

Tan, Beibei ^{[1
]}

机构：

[1] Chinese Acad Agr Sci, State Key Lab Biol Plant Dis & Insect Pests, Inst Plant Protect, Beijing 100193, Peoples R China

[2] Beijing Univ Chinese Med, Sch Chinese Pharm, Beijing 100102, Peoples R China

[3] Beijing City Univ, Dept Biotechnol, Beijing 100094, Peoples R China

来源：

MOLECULES | 2010年 / 15卷 / 05期

基金：

国家高技术研究发展计划(863计划);

关键词：

Wuyiencin; antimicrobial activity; Rhodotorula rubra; Bacillus subtilis; Bacillus megaterium; Escherichia coli; Cladosporium fulvum; Staphylococcus aureus;

D O I：

10.3390/molecules15053179

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The aim of this study was to evaluate the antimicrobial activity of Wuyiencin fractions with different polarities against six indicator microorganisms: Rhodotorula rubra, Bacillus subtilis, Bacillus megaterium, Escherichia coli, Cladosporium fulvum and Staphylococcus aureus. The fermentation broth of Wuyiencin was submitted to AB-8 macroporous adsorptive resin and fractionated with solvents of different polarity. The fraction eluted with water had remarkably antimicrobial activity against all the microorganisms investigated except for C. fulvum and S. aureus (MIC <= 0.0625 mg/mL), probably due to the presence of active components. The fraction eluted with methanol showed potential antimicrobial activity against all the test microorganisms except for R. rubra, with MIC values of 0.5 and 2 mg/mL. In conclusion, fractions eluted with water and methanol, respectively, represent the main active-part of Wuyiencin, and could be emphasized for agricultural applications in the future.

引用

页码：3179 / 3185

页数：7

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