Candida spp. vertebral osteomyelitis

被引:2
作者
Richaud, C. [1 ]
Lefort, A. [1 ]
机构
[1] Hop Beaujon, Serv Med Interne, F-92110 Clichy, France
来源
ANTIBIOTIQUES | 2010年 / 12卷 / 01期
关键词
Vertebral Osteomyelitis; Candida spp; LIPOSOMAL AMPHOTERICIN-B; BLOOD-STREAM INFECTIONS; OF-THE-LITERATURE; ALBICANS SPONDYLODISCITIS; LUMBAR SPINE; FLUCONAZOLE; PATIENT; THERAPY; CASPOFUNGIN; MANAGEMENT;
D O I
10.1016/j.antib.2010.01.002
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Candida spp. vertebral osteomyelitis is rare and remains poorly understood. Most patients have risk factors for candidemia or are intravenous drug addicts. Clinical presentation is unspecific: back pain, and sometimes fever. The microbiological diagnosis requires culture of a biopsy specimen. Radiological features are unspecific. Medical treatment is the first step of therapeutic management, based on prolonged courses of fluconazole or liposomal amphotericine B. Surgery is indicated in case of complication (instable location, spinal cord impingement), or to obtain biopsy specimens. The prognosis is good in the absence of significant comorbidity. (C) 2010 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:61 / 65
页数:5
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