1,5-Benzodiazepine derivatives of 3-arylsydnones:: synthesis and antimicrobial activity of 3-aryl-4-[2′-aryl-2′,4′,6′,7′-tetrahydro-(1′H)-1′,5′-benzodiazepine-4′-yl]sydnones

被引：55

作者：

Kavali, JR ^{[1
]}

Badami, BV ^{[1
]}

机构：

[1] Karnatak Univ, Post Grad Dept Studies Chem, Dharwad 580003, Karnataka, India

来源：

FARMACO | 2000年 / 55卷 / 05期

关键词：

benzodiazepine derivatives; 3-arylsydnones; antimicrobial activity;

D O I：

10.1016/S0014-827X(00)00061-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The alpha-beta-unsaturated ketones of 3-arylsydnones (Ia-y) were treated with 1,2-phenylenediamine to obtain the 3-aryl-4-[2'-aryl-2',4',6',7'-tetrahydro-(1'H)-1',5'-benzodiazepine-4'-yl]sydnones (IIa-y) in high yield. All the new compounds synthesised were screened for antibacterial and antifungal activities. (C) 2000 Elsevier Science S.A. All rights reserved.

引用

页码：406 / 409

页数：4

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