Can neural stem cells be used as therapeutic vehicles in the treatment of brain tumors?

被引：18
|
作者：
Noble, M [1 ]
机构：
[1] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT 84112 USA
来源：
NATURE MEDICINE | 2000年 / 6卷 / 04期
关键词：
D O I：
10.1038/74610
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The most exciting recently developed therapeutic approaches for glioma and other types of nervous system tumors involve combinations of immune-therapy and neural stem cells. But we must bear in mind that the human brain differs greatly from the mouse brain, and that approaches that are effective in animal models may not always be safe for humans.
引用
收藏
页码：369 / 370
页数：2
相关论文
共 50 条
  • [11] From neural stem cells to brain tumors: a genetic analysis
    Laurenson, A. S.
    Saini, N.
    Jiang, Y.
    Fischer, A.
    Knoblich, J.
    Reichert, H.
    JOURNAL OF NEUROGENETICS, 2012, 26 : 30 - 30
  • [12] Characterization of adult neural stem cells and their relation to brain tumors
    Jackson, Erica L.
    Alvarez-Buylla, Arturo
    CELLS TISSUES ORGANS, 2008, 188 (1-2) : 212 - 224
  • [13] Human neural stem cells can target and deliver therapeutic genes to breast cancer brain metastases
    Jin, Juyoun
    Joo, Kyeung Min
    Kang, Bong Gu
    Kim, Mi Hyun
    Lee, Sejeong
    Jung, Yong
    Seo, Yun-Jee
    Jo, Mi-Young
    Kim, Seung Up
    Nam, Do-Hyun
    CANCER RESEARCH, 2009, 69
  • [14] Human Neural Stem Cells Can Target and Deliver Therapeutic Genes to Breast Cancer Brain Metastases
    Joo, Kyeung Min
    Park, In H.
    Shin, Ji Y.
    Jin, Juyoun
    Kang, Bong Gu
    Kim, Mi Hyun
    Lee, Se Jeong
    Jo, Mi-young
    Kim, Seung U.
    Nam, Do-Hyun
    MOLECULAR THERAPY, 2009, 17 (03) : 570 - 575
  • [15] HUMAN NEURAL STEM CELLS CAN TARGET AND DELIVER THERAPEUTIC GENES TO BREAST CANCER BRAIN METASTASES
    Joo, Kyeung Min
    Lee, Jeongwu
    Jin, Juyoun
    Kang, Bong Gu
    Kong, Doo-Sik
    Lee, Jung-Ii
    Hong, Seung-Chyul
    Kim, Jong Hyun
    Nam, Do-Hyun
    NEURO-ONCOLOGY, 2009, 11 (06) : 927 - 927
  • [16] The Therapeutic Potential of Neural Stem Cells in Traumatic Brain Injuries
    Kabatas, Serdar
    Cansever, Tufan
    Civelek, Erdinc
    Yilmaz, Cem
    CURRENT SIGNAL TRANSDUCTION THERAPY, 2011, 6 (03) : 327 - 336
  • [17] HERPES-LOADED STEM CELLS USED TO KILL BRAIN TUMORS
    不详
    STEM CELLS TRANSLATIONAL MEDICINE, 2014, 3 (07) : XV - XV
  • [18] Mathematical modeling of therapeutic neural stem cell migration in mouse brain with and without brain tumors
    Gomez, Justin
    Holmes, Nathanael
    Hansen, Austin
    Adhikarla, Vikram
    Gutova, Margarita
    Rockne, Russell C.
    Cho, Heyrim
    MATHEMATICAL BIOSCIENCES AND ENGINEERING, 2022, 19 (03) : 2592 - 2615
  • [19] Adenosine potentiates the therapeutic effects of neural stem cells expressing cytosine deaminase against metastatic brain tumors
    Kang, Wonyoung
    Seol, Ho Jun
    Seong, Dong-Ho
    Kim, Jandi
    Kim, Yonghyun
    Kim, Seung U.
    Nam, Do-Hyun
    Joo, Kyeung Min
    ONCOLOGY REPORTS, 2013, 30 (03) : 1101 - 1106
  • [20] Stem cells as therapeutic vehicles for the treatment of high-grade gliomas
    Binello, Emanuela
    Germano, Isabelle M.
    NEURO-ONCOLOGY, 2012, 14 (03) : 256 - 265
12345