Synthesis and characterisation of the first transition metal complex of zoxazolamine (2-amino-5-chlorobenzoxazole):: the X-ray crystal structure determination of [ZnCl2(η1-Nbenzoxazole-2-amino-5-chlorobenzoxazole)2]

被引：26
作者：
Decken, A
Gossage, RA
机构：
[1] Acadia Univ, Dept Chem, David Upton Hill Labs Inorgan Chem, Wolfville, NS B4P 2R6, Canada
[2] Univ New Brunswick, Dept Chem, Fredericton, NB E3B 6E2, Canada
来源：
JOURNAL OF INORGANIC BIOCHEMISTRY | 2005年 / 99卷 / 02期
基金：
加拿大自然科学与工程研究理事会;
关键词：
zoxazolamine; 2-amino-5-chlorobenzoxazole; 5-chloro-2-benzoxazolamine; zinc complex; X-ray crystal structure; oxazole; benzoxazole; deflexol; flexilon; flexin; zoxamin; zoxine; McN-485;
D O I：
10.1016/j.jinorgbio.2004.09.003
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The synthesis and characterisation (NMR, X-ray, elemental analysis) of the first transition metal complex of Zoxazolamine (1: 2-amino- 5-chlorobenzoxazole), viz. [ZnCl2(1)(2)] (2) is described; complex 2 is obtained in 77% yield from the treatment of 1 with ZnCl2 in acetone solution. The Zn compound is a mononuclear species (X-ray) with a distorted tetrahedral array of ligands around the metal centre with the title ligand bound to Zn via the benzoxazole ring N-atom. The structural properties of 2 are discussed in relation to other mononuclear Zn halide complexes. (C) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码：664 / 667
页数：4
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