The potential of a 2Tone trainer to help patients use their metered-dose inhalers

被引:57
作者
Al-Showair, Raid A. M.
Pearson, Stanley B.
Chrystyn, Henry [1 ]
机构
[1] Univ Bradford, Sch Pharm, Bradford BD7 1DP, W Yorkshire, England
[2] Univ Bradford, Inst Pharmaceut Innovat, Bradford BD7 1DP, W Yorkshire, England
[3] Leeds Gen Infirm, Dept Resp Med, Leeds, W Yorkshire, England
关键词
asthma quality of life; metered dose inhaler; slow inhalation rate; 2Tone trainer;
D O I
10.1378/chest.06-2765
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Background: Many patients have problems using the correct inhalation technique when they use their metered-dose inhalers (MDIs). We have investigated whether a training aid (2Tone Trainer [2T]; Canday Medical Ltd; Newmarket, UK) helps to maintain the correct inhaler technique after patients leave the clinic Methods: Ethics committee approval was obtained, and patients gave consent. Asthmatic patients who had been prescribed an MDI had their inhalation technique assessed. Their peak inhalation flow (PIF) when using their MDI, FEV1 and the juniper asthma quality of life questionnaire (AQLQ) score were measured. Those patients using the recommended MDT technique were the good-technique (GT) group. The remainder were randomized to receive verbal training (VT) or VT plus the 2T to improve their MDI technique. All patients returned 6 weeks later. Results: There were 36, 35, and 36 asthmatic patients, respectively, who completed the GT, VT, and 2T procedures. FEV1 did not change within all groups between visit 1 and 2. PIF and AQLQ score did not change in the GT group. In the VT and 2T groups, the AQLQ score increased by mean differences of 0.33 (95% confidence interval [CI], 0.14 to 0.53; p < 0.001) and 0.74 (95% CI, 0.62 to 0.86; p < 0.001). At visit 1, all patients in the VT and 2T groups inhaled > 90 L/min decreasing to 12 patients and I patient, respectively, at visit 2 (p < 0.001 both groups). The overall changes in the 2T group for PIF and AQLQ score, between visits I and 2, were significantly (p < 0.001) greater than the corresponding changes in the VT group. Conclusion: The 2T helps patients to maintain the recommended MDI technique posttraining with improvements in AQLQ score.
引用
收藏
页码:1776 / 1782
页数:7
相关论文
共 34 条
[1]  
Brocklebank D, 2001, Health Technol Assess, V5, P1
[2]   Inhalation profiles in asthmatics and COPD patients: Reproducibility and effect of instruction [J].
Broeders, MEAC ;
Molema, J ;
Hop, WCJ ;
Folgering, HTM .
JOURNAL OF AEROSOL MEDICINE-DEPOSITION CLEARANCE AND EFFECTS IN THE LUNG, 2003, 16 (02) :131-141
[3]  
CARSTAIRS JR, 1985, AM REV RESPIR DIS, V132, P541
[4]  
CHRYSTYN H, 2002, AM J RESP CRIT CARE, V105, pA190
[5]  
CROMPTON GK, 1982, EUR J RESPIR DIS, V63, P101
[6]   Device selection and outcomes of aerosol therapy: Evidence-based guidelines [J].
Dolovich, MB ;
Ahrens, RC ;
Hess, DR ;
Anderson, P ;
Dhand, R ;
Rau, JL ;
Smaldone, GC ;
Guyatt, G .
CHEST, 2005, 127 (01) :335-371
[7]   AEROSOL DEPOSITION IN THE HUMAN LUNG FOLLOWING ADMINISTRATION FROM A MICROPROCESSOR-CONTROLLED PRESSURIZED METERED-DOSE INHALER [J].
FARR, SJ ;
ROWE, AM ;
RUBSAMEN, R ;
TAYLOR, G .
THORAX, 1995, 50 (06) :639-644
[8]   Evaluation of the impact of a pharmaceutical care program in children with asthma [J].
González-Martin, G ;
Joo, I ;
Sánchez, I .
PATIENT EDUCATION AND COUNSELING, 2003, 49 (01) :13-18
[9]  
Hesselink AE, 2001, SCAND J PRIM HEALTH, V19, P255
[10]   INVESTIGATIONS OF AN OPTIMAL INHALER TECHNIQUE WITH THE USE OF URINARY SALBUTAMOL EXCRETION AS A MEASURE OF RELATIVE BIOAVAILABILITY TO THE LUNG [J].
HINDLE, M ;
NEWTON, DAG ;
CHRYSTYN, H .
THORAX, 1993, 48 (06) :607-610