Enantioselective Diels-Alder Cycloadditions with β-Substituted Pyrazolidinone Propiolimides

被引：6
|
作者：
Sibi, Mukund P. [1 ]
Cruz, Wilfredo, Jr. [1 ]
Stanley, Levi M. [1 ]
机构：
[1] N Dakota State Univ, Dept Chem & Mol Biol, Fargo, ND 58105 USA
来源：
SYNLETT | 2010年 / 06期
关键词：
Diels-Alder cycloaddition; acetylenic dienophile; enantioselective; pyrazolidinone; chiral Lewis acid; LEWIS-ACID CATALYSTS; CHIRAL RELAY; LIGANDS; CYCLOPENTADIENE; TEMPLATES; OLEFINS; EXO;
D O I：
10.1055/s-0029-1219538
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Chiral Lewis acid catalyzed Diels-Alder cycloadditions between beta-substituted pyrazolidinone propiolimides and cyclic dienes have been studied. A catalyst prepared from Sc(OTf)(3) and t-Bu-pybox ligand promotes the formation of enantioenriched diene cycloadducts in moderate to high yield and good enantioselectivity from the reactions of acetylenic dienophiles and cyclic dienes.
引用
收藏
页码：889 / 892
页数：4
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