Association of leukemia genetics with response to venetoclax and hypomethylating agents in relapsed/refractory acute myeloid leukemia

被引：90

作者：

Aldoss, Ibrahim ^{[1
]}

Yang, Dongyun ^{[2
]}

Pillai, Raju ^{[3
]}

Sanchez, James F. ^{[1
]}

Mei, Matthew ^{[1
]}

Aribi, Ahmed ^{[1
]}

Ali, Haris ^{[1
]}

Sandhu, Karamjeet ^{[1
]}

Al Malki, Monzr M. ^{[1
]}

Salhotra, Amandeep ^{[1
]}

Khaled, Samer ^{[1
]}

Sun, Weili ^{[4
]}

O'Donnell, Margaret ^{[1
]}

Snyder, David ^{[1
]}

Nakamura, Ryotaro ^{[1
]}

Stein, Anthony S. ^{[1
]}

Forman, Stephen J. ^{[3
]}

Marcucci, Guido ^{[1
]}

Pullarkat, Vinod ^{[1
]}

机构：

[1] City Hope Med Ctr, Gehr Family Ctr Leukemia Res, Dept Hematol & Hematopoiet Cell Transplantat, 1500 East Duarte Rd, Duarte, CA 91010 USA

[2] City Hope Med Ctr, Dept Informat Sci, Duarte, CA USA

[3] City Hope Med Ctr, Dept Pathol, Duarte, CA USA

[4] City Hope Med Ctr, Dept Pediat, Duarte, CA USA

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 2019年 / 94卷 / 10期

基金：

美国国家卫生研究院;

关键词：

MUTATIONS; DIAGNOSIS;

D O I：

10.1002/ajh.25567

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：E253 / E255

页数：3

共 6 条

[1] Efficacy of the combination of venetoclax and hypomethylating agents in relapsed/refractory acute myeloid leukemia [J].

Aldoss, Ibrahim ;

Yang, Dongyun ;

Aribi, Ahmed ;

Ali, Haris ;

Sandhu, Karamjeet ;

Al Malki, Monzr M. ;

Mei, Matthew ;

Salhotra, Amandeep ;

Khaled, Samer ;

Nakamura, Ryotaro ;

Snyder, David ;

O'Donnell, Margaret ;

Stein, Anthony S. ;

Forman, Stephen J. ;

Marcucci, Guido ;

Pullarkat, Vinod .

HAEMATOLOGICA, 2018, 103 (09) :E404-E407

[2] TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients [J].

Bejar, Rafael ;

Lord, Allegra ;

Stevenson, Kristen ;

Bar-Natan, Michal ;

Perez-Ladaga, Albert ;

Zaneveld, Jacques ;

Wang, Hui ;

Caughey, Bennett ;

Stojanov, Petar ;

Getz, Gad ;

Garcia-Manero, Guillermo ;

Kantarjian, Hagop ;

Chen, Rui ;

Stone, Richard M. ;

Neuberg, Donna ;

Steensma, David P. ;

Ebert, Benjamin L. .

BLOOD, 2014, 124 (17) :2705-2712

[3] Genomics of Acute Myeloid Leukemia Diagnosis and Pathways [J].

Bullinger, Lars ;

Doehner, Konstanze ;

Doehner, Hartmut .

JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (09) :934-946

[4] Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia [J].

DiNardo, Courtney D. ;

Pratz, Keith ;

Pullarkat, Vinod ;

Jonas, Brian A. ;

Arellano, Martha ;

Becker, Pamela S. ;

Frankfurt, Olga ;

Konopleva, Marina ;

Wei, Andrew H. ;

Kantarjian, Hagop M. ;

Xu, Tu ;

Hong, Wan-Jen ;

Chyla, Brenda ;

Potluri, Jalaja ;

Pollyea, Daniel A. ;

Letai, Anthony .

BLOOD, 2019, 133 (01) :7-17

[5] Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel [J].

Doehner, Hartmut ;

Estey, Elihu ;

Grimwade, David ;

Amadori, Sergio ;

Appelbaum, Frederick R. ;

Buechner, Thomas ;

Dombret, Herve ;

Ebert, Benjamin L. ;

Fenaux, Pierre ;

Larson, Richard A. ;

Levine, Ross L. ;

Lo-Coco, Francesco ;

Naoe, Tomoki ;

Niederwieser, Dietger ;

Ossenkoppele, Gert J. ;

Sanz, Miguel ;

Sierra, Jorge ;

Tallman, Martin S. ;

Tien, Hwei-Fang ;

Wei, Andrew H. ;

Lowenberg, Bob ;

Bloomfield, Clara D. .

BLOOD, 2017, 129 (04) :424-447

[6] Impact of molecular mutations on treatment response to DNMT inhibitors in myelodysplasia and related neoplasms [J].

Traina, F. ;

Visconte, V. ;

Elson, P. ;

Tabarroki, A. ;

Jankowska, A. M. ;

Hasrouni, E. ;

Sugimoto, Y. ;

Szpurka, H. ;

Makishima, H. ;

O'Keefe, C. L. ;

Sekeres, M. A. ;

Advani, A. S. ;

Kalaycio, M. ;

Copelan, E. A. ;

Saunthararajah, Y. ;

Saad, S. T. Olalla ;

Maciejewski, J. P. ;

Tiu, R. V. .

LEUKEMIA, 2014, 28 (01) :78-87

← 1 →