Type 2 innate lymphoid cells in induced sputum from children with severe asthma

被引:118
作者
Nagakumar, Prasad [1 ,2 ]
Denney, Laura [1 ]
Fleming, Louise [1 ,2 ]
Bush, Andrew [1 ,2 ]
Lloyd, Clare M. [1 ]
Saglani, Sejal [1 ,2 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, London, England
[2] Royal Brompton Hosp, London SW3 6LY, England
基金
英国惠康基金; 英国医学研究理事会;
关键词
INFLAMMATION; CYTOKINES; IL-33;
D O I
10.1016/j.jaci.2015.06.038
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:624 / +
页数:10
相关论文
共 13 条
[1]   CD34+ hemopoietic progenitor cells are potent effectors of allergic inflammation [J].
Allakhverdi, Zoulfia ;
Comeau, Michael R. ;
Smith, Dirk E. ;
Toy, Dean ;
Endam, Leandra Mfuna ;
Desrosiers, Martin ;
Liu, Yong-Jun ;
Howie, Karen J. ;
Denburg, Judah A. ;
Gauvreau, Gail M. ;
Delespesse, Guy .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2009, 123 (02) :472-478
[2]   Pediatric severe asthma is characterized by eosinophilia and remodeling without TH2 cytokines [J].
Bossley, Cara J. ;
Fleming, Louise ;
Gupta, Atul ;
Regamey, Nicolas ;
Frith, Jennifer ;
Oates, Timothy ;
Tsartsali, Lemonia ;
Lloyd, Clare M. ;
Bush, Andrew ;
Saglani, Sejal .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2012, 129 (04) :974-U469
[3]   The importance of nurse-led home visits in the assessment of children with problematic asthma [J].
Bracken, M. ;
Fleming, L. ;
Hall, P. ;
Van Stiphout, N. ;
Bossley, C. ;
Biggart, E. ;
Wilson, N. M. ;
Bush, A. .
ARCHIVES OF DISEASE IN CHILDHOOD, 2009, 94 (10) :780-784
[4]   Molecular phenotyping of severe asthma using pattern recognition of bronchoalveolar lavage-derived cytokines [J].
Brasier, Allan R. ;
Victor, Sundar ;
Boetticher, Gary ;
Ju, Hyunsu ;
Lee, Chang ;
Bleecker, Eugene R. ;
Castro, Mario ;
Busse, William W. ;
Calhoun, William J. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2008, 121 (01) :30-37
[5]   Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33 [J].
Christianson, Christina A. ;
Goplen, Nicholas P. ;
Zafar, Iram ;
Irvin, Chaoyu ;
Good, James T., Jr. ;
Rollins, Donald R. ;
Gorentla, Balachandra ;
Liu, Weimin ;
Gorska, Magdalena M. ;
Chu, HongWei ;
Martin, Richard J. ;
Alam, Rafeul .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2015, 136 (01) :59-U142
[6]   GATA binding protein 3+ group 2 innate lymphoid cells are present in cord blood and in higher proportions in male than in female neonates [J].
Forsberg, Anna ;
Bengtsson, Mathias ;
Eringfalt, Anna ;
Ernerudh, Jan ;
Mjosberg, Jenny ;
Jenmalm, Maria C. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 134 (01) :228-230
[7]   IL-33-Dependent Type 2 Inflammation during Rhinovirus-induced Asthma Exacerbations In Vivo [J].
Jackson, David J. ;
Makrinioti, Heidi ;
Rana, Batika M. J. ;
Shamji, Betty W. H. ;
Trujillo-Torralbo, Maria-Belen ;
Footitt, Joseph ;
Del-Rosario, Jerico ;
Telcian, Aurica G. ;
Nikonova, Alexandra ;
Zhu, Jie ;
Aniscenko, Julia ;
Gogsadze, Leila ;
Bakhsoliani, Eteri ;
Traub, Stephanie ;
Dhariwal, Jaideep ;
Porter, James ;
Hunt, Duncan ;
Hunt, Toby ;
Hunt, Trevor ;
Stanciu, Luminita A. ;
Khaitov, Musa ;
Bartlett, Nathan W. ;
Edwards, Michael R. ;
Kon, Onn Min ;
Mallia, Patrick ;
Papadopoulos, Nikolaos G. ;
Akdis, Cezmi A. ;
Westwick, John ;
Edwards, Matthew J. ;
Cousins, David J. ;
Walton, Ross P. ;
Johnston, Sebastian L. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 190 (12) :1373-1382
[8]   Flow cytometry of sputum: assessing inflammation and immune response elements in the bronchial airways [J].
Lay, John C. ;
Peden, David B. ;
Alexis, Neil E. .
INHALATION TOXICOLOGY, 2011, 23 (07) :392-406
[9]   Type 2 innate lymphoid cells-new members of the "type 2 franchise" that mediate allergic airway inflammation [J].
Mjosberg, Jenny ;
Spits, Hergen .
EUROPEAN JOURNAL OF IMMUNOLOGY, 2012, 42 (05) :1093-1096
[10]   Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma [J].
Peters, Michael C. ;
Mekonnen, Zesemayat K. ;
Yuan, Shaopeng ;
Bhakta, Nirav R. ;
Woodruff, Prescott G. ;
Fahy, John V. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 133 (02) :388-U181