Stress-induced obesity and the emotional nervous system

被引:530
作者
Dallman, Mary F. [1 ]
机构
[1] Univ Calif San Francisco, Dept Physiol, San Francisco, CA 94143 USA
关键词
FOOD-INTAKE; ENERGY-BALANCE; WEIGHT CHANGE; GLUCOCORTICOID-RECEPTOR; EATING-DISORDERS; DAILY HASSLES; LARD INTAKE; HPA AXIS; BRAIN; INSULIN;
D O I
10.1016/j.tem.2009.10.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Stress and emotional brain networks foster eating behaviors that can lead to obesity. The neural networks underlying the complex interactions among stressors, body, brain and food intake are now better understood. Stressors, by activating a neural stress-response network, bias cognition toward increased emotional activity and degraded executive function. This causes formed habits to be used rather than a cognitive appraisal of responses. Stress also induces secretion of glucocorticoids, which increases motivation for food, and insulin, which promotes food intake and obesity. Pleasurable feeding then reduces activity in the stress-response network, reinforcing the feeding habit. These effects of stressors emphasize the importance of teaching mental reappraisal techniques to restore responses from habitual to thoughtful, thus battling stress-induced obesity.
引用
收藏
页码:159 / 165
页数:7
相关论文
共 105 条
  • [91] Relationship between stress, eating behavior, and obesity
    Torres, Susan J.
    Nowson, Caryl A.
    [J]. NUTRITION, 2007, 23 (11-12) : 887 - 894
  • [92] *TRUST AM HLTH RW, 2009, TRUST AM HLTH
  • [93] Neural regulation of endocrine and autonomic stress responses
    Ulrich-Lai, Yvonne M.
    Herman, James P.
    [J]. NATURE REVIEWS NEUROSCIENCE, 2009, 10 (06) : 397 - 409
  • [94] Neuroendocrine control of food intake
    Valassi, Elena
    Scacchi, Massimo
    Cavagnini, Francesco
    [J]. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 2008, 18 (02) : 158 - 168
  • [95] Neuroimaging in Eating Disorders and Obesity: Implications for Research
    Van den Eynde, Frederique
    Treasure, Janet
    [J]. CHILD AND ADOLESCENT PSYCHIATRIC CLINICS OF NORTH AMERICA, 2009, 18 (01) : 95 - +
  • [96] Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology
    Volkow, Nora D.
    Wang, Gene-Jack
    Fowler, Joanna S.
    Telang, Frank
    [J]. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2008, 363 (1507) : 3191 - 3200
  • [97] Emotions and eating. Self-reported and experimentally induced changes in food intake under stress
    Wallis, D. J.
    Hetherington, M. M.
    [J]. APPETITE, 2009, 52 (02) : 355 - 362
  • [98] Hepatic branch vagotomy, like insulin replacement, promotes voluntary lard intake in streptozotocin-diabetic rats
    Warne, James P.
    Foster, Michelle T.
    Horneman, Hart F.
    Pecoraro, Norman C.
    Ginsberg, Abigail B.
    Akana, Susan F.
    Dallman, Mary F.
    [J]. ENDOCRINOLOGY, 2007, 148 (07) : 3288 - 3298
  • [99] Disengaging insulin from corticosterone: roles of each on energy intake and disposition
    Warne, James P.
    Akana, Susan F.
    Ginsberg, Abigail B.
    Horneman, Hart F.
    Pecoraro, Norman C.
    Dallman, Mary F.
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2009, 296 (05) : R1366 - R1375
  • [100] Dendritic architecture of the von Economo neurons
    Watson, K. K.
    Jones, T. K.
    Allman, J. M.
    [J]. NEUROSCIENCE, 2006, 141 (03) : 1107 - 1112