Stress-induced obesity and the emotional nervous system

被引:530
作者
Dallman, Mary F. [1 ]
机构
[1] Univ Calif San Francisco, Dept Physiol, San Francisco, CA 94143 USA
关键词
FOOD-INTAKE; ENERGY-BALANCE; WEIGHT CHANGE; GLUCOCORTICOID-RECEPTOR; EATING-DISORDERS; DAILY HASSLES; LARD INTAKE; HPA AXIS; BRAIN; INSULIN;
D O I
10.1016/j.tem.2009.10.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Stress and emotional brain networks foster eating behaviors that can lead to obesity. The neural networks underlying the complex interactions among stressors, body, brain and food intake are now better understood. Stressors, by activating a neural stress-response network, bias cognition toward increased emotional activity and degraded executive function. This causes formed habits to be used rather than a cognitive appraisal of responses. Stress also induces secretion of glucocorticoids, which increases motivation for food, and insulin, which promotes food intake and obesity. Pleasurable feeding then reduces activity in the stress-response network, reinforcing the feeding habit. These effects of stressors emphasize the importance of teaching mental reappraisal techniques to restore responses from habitual to thoughtful, thus battling stress-induced obesity.
引用
收藏
页码:159 / 165
页数:7
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