Molar-scale synthesis of 1,2:5,6-Di-O-isopropylidene-α-D-allofuranose:: DMSO oxidation of 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose and subsequent sodium borohydride reduction

被引：16

作者：

Christensen, SM ^{[1
]}

Hansen, HF ^{[1
]}

Koch, T ^{[1
]}

机构：

[1] Santaris Pharma AS, DK-2970 Horsholm, Denmark

来源：

ORGANIC PROCESS RESEARCH & DEVELOPMENT | 2004年 / 8卷 / 05期

关键词：

D O I：

10.1021/op049903t

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two variants of oxidation with DMSO followed by sodium borohydride reduction have been investigated to make the synthesis of 1,2:5,6-di-O-isopropylidene-alpha-D-allofuranose (4) suitable for large-scale manufacturing.

引用

页码：777 / 780

页数：4

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