Quality assurance in rectal cancer treatment in the Netherlands: A catch up compared to colon cancer treatment

被引：25

作者：

van Gijn, W. ^{[1
]}

Krijnen, P. ^{[2
]}

Lemmens, V. E. P. P. ^{[3
]}

den Dulk, M. ^{[4
]}

Putter, H. ^{[5
]}

van de Velde, C. J. H. ^{[1
]}

机构：

[1] Leiden Univ, Med Ctr, Dept Surg, NL-2300 RC Leiden, Netherlands

[2] Comprehens Canc Ctr W IKW, Leiden Canc Registry, Leiden, Netherlands

[3] Comprehens Canc Ctr S IKZ, Eindhoven Canc Registry, Eindhoven, Netherlands

[4] Haga Hosp, Dept Surg, The Hague, Netherlands

[5] Leiden Univ, Med Ctr, Dept Stat, NL-2300 RC Leiden, Netherlands

来源：

EJSO | 2010年 / 36卷 / 04期

关键词：

Rectal cancer; Colon cancer; Colorectal cancer; quality assurance; outcome assessment; Survival; TOTAL MESORECTAL EXCISION; PREOPERATIVE RADIOTHERAPY; SURGICAL RESECTION; LOCAL RECURRENCE; SURVIVAL; SURGERY; TRIAL;

D O I：

10.1016/j.ejso.2009.10.010

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: In the Netherlands, the Total Mesorectal Excision (TME) surgical technique for rectal cancer was introduced together with pre-operative radiotherapy in a quality controlled manner within the framework of the TME trial (1996-1999). The aim of this study is to examine the effects of the structural changes in rectal cancer care on survival compared to colon cancer for patients treated before, during and after the TME trial. Method: We compared overall survival of all patients with curatively resected colon (n = 15,266) and rectal cancer (n = 5839) in the regions of Comprehensive Cancer Centres South and West between 1990 and 2005, adjusting for prognostic variables. Results: In the pre-trial period, rectal cancer had a significant lower survival compared to colon cancer (HR 1.248, P < 0.01). However, in the post-trial period, survival after rectal cancer was similar to colon cancer (HR 0.987, n.s.). Conclusion: Although survival improved significantly for both colon and rectal cancer in the last 15 years, the substantially worse results after rectal cancer have been eliminated. This study shows the lasting effects that structural surgical training and quality assurance can have on survival outcome. (c) 2009 Elsevier Ltd. All rights reserved.

引用

页码：340 / 344

页数：5

共 15 条

[1] Improved overall survival for patients with rectal cancer since 1990: The effects of TME surgery and pre-operative radiotherapy [J].

den Dulk, Marcel ;

Krijnen, Pieta ;

Marijnen, Corrie A. M. ;

Rutten, Harm J. ;

van de Poll-Franse, Lonneke V. ;

Putter, Hein ;

Kranenbarg, Elma Meershoek-Klein ;

Jansen-Landheer, Marlies L. E. A. ;

Coebergh, Jan-Willem W. ;

van de Velde, Cornelis J. H. .

EUROPEAN JOURNAL OF CANCER, 2008, 44 (12) :1710-1716

[2] Survival of colorectal cancer patients in Europe during the period 1978-1989 [J].

Gatta, G ;

Faivre, J ;

Capocaccia, R ;

de Leon, AP .

EUROPEAN JOURNAL OF CANCER, 1998, 34 (14) :2176-2183

[3] Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer [J].

Kapiteijn, E ;

Marijnen, CAM ;

Nagtegaal, ID ;

Putter, H ;

Steup, WH ;

Wiggers, T ;

Rutten, HJT ;

Pahlman, L ;

Glimelius, B ;

van Krieken, JHJM ;

Leer, JWH ;

van de Velde, CJH .

NEW ENGLAND JOURNAL OF MEDICINE, 2001, 345 (09) :638-646

[4] Improved survival after resectable non-cardia gastric cancer in the Netherlands: The importance of surgical training and quality control [J].

Krijnen, P. ;

den Dulk, M. ;

Kranenbarg, E. Meershoek-Klein ;

Jansen-Landheer, M. L. E. A. ;

van de Velde, C. J. H. .

EJSO, 2009, 35 (07) :715-720

[5] Cost effectiveness of adding folinic acid to fluorouracil plus levamisole as adjuvant chemotherapy in patients with colon cancer in Germany [J].

Monz, BUM ;

König, HH ;

Leidl, R ;

Staib, L ;

Link, KH .

PHARMACOECONOMICS, 2003, 21 (10) :709-719

[6] Guest editorial - Surgical quality assurance in breast, gastric and rectal cancer [J].

Peeters, KCMJ ;

van de Velde, CJH .

JOURNAL OF SURGICAL ONCOLOGY, 2003, 84 (03) :107-112

[7] The TME trial after a median follow-up of 6 years - Increased local control but no survival benefit in irradiated patients with resectable rectal carcinoma [J].

Peeters, Koen C. M. J. ;

Marijnen, Corrie A. M. ;

Nagtegaal, Iris D. ;

Kranenbarg, Elma Klein ;

Putter, Hein ;

Wiggers, Theo ;

Rutten, Harm ;

Pahlman, Lars ;

Glimelius, Bengt ;

Leer, Jan Willem ;

van de Velde, Cornelis J. H. .

ANNALS OF SURGERY, 2007, 246 (05) :693-701

[8] LOCAL RECURRENCE OF RECTAL ADENOCARCINOMA DUE TO INADEQUATE SURGICAL RESECTION - HISTOPATHOLOGICAL STUDY OF LATERAL TUMOR SPREAD AND SURGICAL EXCISION [J].

QUIRKE, P ;

DIXON, MF ;

DURDEY, P ;

WILLIAMS, NS .

LANCET, 1986, 2 (8514) :996-999

[9] Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial [J].

Quirke, Phil ;

Steele, Robert ;

Monson, John ;

Grieve, Robert ;

Khanna, Subhash ;

Couture, Jean ;

O'Callaghan, Chris ;

Myint, Arthur Sun ;

Bessell, Eric ;

Thompson, Lindsay C. ;

Parmar, Mahesh ;

Stephens, Richard J. ;

Sebag-Montefiore, David .

LANCET, 2009, 373 (9666) :821-828

[10] EUROCARE-4. Survival of cancer patients diagnosed in 1995-1999. Results and commentary [J].

Sant, Milena ;

Allemani, Claudia ;

Santaquilani, Mariano ;

Knijn, Arnold ;

Marchesi, Francesca ;

Capocaccia, Riccardo .

EUROPEAN JOURNAL OF CANCER, 2009, 45 (06) :931-991

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