The first one-pot 'alkane-like' reactions of carbonyl-containing adamantanes

被引:11
作者
Akhrem, Irena [1 ]
Avetisyan, Dzhul'etta [1 ]
Afanas'eva, Lyudmila [1 ]
Kagramanov, Nikolai [1 ]
Petrovskii, Pavel [1 ]
Orlinkov, Alexander [1 ]
机构
[1] Russian Acad Sci, AN Nesmeyanov Organoelement Cpds Inst, Moscow 119991, Russia
基金
俄罗斯基础研究基金会;
关键词
'Alkane-like' reactions; Synthesis; 1,3-Dicarbonyl-containing adamantane; Superelectrophiles; DIRECTED DRUG CARRIER; POORLY ABSORBED DRUG; 1-ADAMANTANE MOIETY; DERIVATIVES; ACIDS; FAMILY; SUPERACIDS; KETONES; DESIGN;
D O I
10.1016/j.tetlet.2009.12.022
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel 'alkane-like' methodology for the direct and very simple one-pot functionalization of amides and an ester of 1-adamantanecarboxylic acid provides access to new and synthetically challenging 1,3-dicarbonyl-containing adamantanoid compounds with the same or different functional groups. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:907 / 911
页数:5
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