A review of induced pluripotent stem cell, direct conversion by trans-differentiation, direct reprogramming and oligodendrocyte differentiation

被引：30
作者：
Prasad, Ankshita [1 ]
Manivannan, Janani [2 ]
Loong, Daniel T. B. [1 ]
Chua, Soo M. [1 ]
Gharibani, Payam M. [3 ]
All, Angelo H. [1 ,2 ,3 ,4 ,5 ,6 ,7 ]
机构：
[1] Natl Univ Singapore, Singapore Inst Neurotechnol, Div Neurol, Dept Orthopaed Surg Biomed Engn & Med, Singapore 117548, Singapore
[2] Natl Univ Singapore, Med, Div Neurol, Dept Orthoped Surg, Singapore 117548, Singapore
[3] Johns Hopkins Sch Med, Dept Biomed Engn & Neurol, Baltimore, MD USA
[4] Natl Univ Singapore, Div Neurol, Dept Med, Singapore 117548, Singapore
[5] Natl Univ Singapore, Div Neurol, Dept Biomed Engn & Med, Singapore 117548, Singapore
[6] Johns Hopkins Sch Med, Dept Neurol, Baltimore, MD USA
[7] Natl Univ Singapore, Singapore Inst Neurotechnol, Ctr Life Sci, 28 Med Dr,05-COR, Singapore 117456, Singapore
来源：
REGENERATIVE MEDICINE | 2016年 / 11卷 / 02期
关键词：
direct conversion; direct reprogramming; iPSC reprogramming; oligodendrocytes; transdifferentiation; SOMATIC-CELLS; FUNCTIONAL-NEURONS; HUMAN FIBROBLASTS; EFFICIENT GENERATION; MOUSE FIBROBLASTS; IPS CELLS; IN-VITRO; INDUCTION; GENES; CARDIOMYOCYTES;
D O I：
10.2217/rme.16.5
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Rapid progress in the field of stem cell therapy and cellular reprogramming provides convincing evidence of its feasibility in treating a wide range of pathologies through autologous cell replacement therapy. This review article describes in detail on three widely used approaches of somatic cell reprogramming: induced pluripotent stem cells, direct conversion and direct reprogramming, in the context of demyelination in the CNS. The potential limitations of each reprogramming technique are reviewed along with their distinct molecular approach to reprogramming. This is followed by an analysis on the scopes and challenges of its translational applications in deriving oligodendrocyte progenitor cells and oligodendrocytes for cell replacement treatment of demyelinating conditions in the CNS.
引用
收藏
页码：181 / 191
页数：11
相关论文
共 50 条
[41]   Reprogram or Reboot: Small Molecule Approaches for the Production of Induced Pluripotent Stem Cells and Direct Cell Reprogramming [J].
Jung, Da-Woon ;
Kim, Woong-Hee ;
Williams, Darren Reece .
ACS CHEMICAL BIOLOGY, 2014, 9 (01) :80-95
[42]   Key Regulators of Cardiovascular Differentiation and Regeneration: Harnessing the Potential of Direct Reprogramming to Treat Heart Failure [J].
Ieda, Masaki .
JOURNAL OF CARDIAC FAILURE, 2020, 26 (01) :80-84
[43]   The use of a SOX10 reporter toward ameliorating oligodendrocyte lineage differentiation from human induced pluripotent stem cells [J].
Piscopo, Valerio E. C. ;
Chapleau, Alexandra ;
Blaszczyk, Gabriela J. ;
Sirois, Julien ;
You, Zhipeng ;
Soubannier, Vincent ;
Chen, Carol X. -Q. ;
Bernard, Genevieve ;
Antel, Jack P. ;
Durcan, Thomas M. .
GLIA, 2024, 72 (06) :1165-1182
[44]   Cell Fusion Enhances Mesendodermal Differentiation of Human Induced Pluripotent Stem Cells [J].
Qin, Jie ;
Sontag, Stephanie ;
Lin, Qiong ;
Mitzka, Saskia ;
Leisten, Isabelle ;
Schneider, Rebekka K. ;
Wang, Xiaoying ;
Jauch, Anna ;
Peitz, Michael ;
Bruestle, Oliver ;
Wagner, Wolfgang ;
Zhao, Robert Chunhua ;
Zenke, Martin .
STEM CELLS AND DEVELOPMENT, 2014, 23 (23) :2875-2882
[45]   Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells [J].
Zwi, Limor ;
Caspi, Oren ;
Arbel, Gil ;
Huber, Irit ;
Gepstein, Amira ;
Park, In-Hyun ;
Gepstein, Lior .
CIRCULATION, 2009, 120 (15) :1513-1523
[46]   Transcription Factor-Directed Re-wiring of Chromatin Architecture for Somatic Cell Nuclear Reprogramming toward trans-Differentiation [J].
Dall'Agnese, Alessandra ;
Caputo, Luca ;
Nicoletti, Chiara ;
di Iulio, Julia ;
Schmitt, Anthony ;
Gatto, Sole ;
Diao, Yarui ;
Ye, Zhen ;
Forcato, Mattia ;
Perera, Ranjan ;
Bicciato, Silvio ;
Telenti, Amalio ;
Ren, Bing ;
Puri, Pier Lorenzo .
MOLECULAR CELL, 2019, 76 (03) :453-+
[47]   A biophysical approach to quantify skeletal stem cells trans-differentiation as a model for the study of osteoporosis [J].
Petecchia, L. ;
Viti, F. ;
Sbrana, F. ;
Vassalli, M. ;
Gavazzo, P. .
BIOPHYSICAL CHEMISTRY, 2017, 229 :84-92
[48]   Adult stem cells and their trans-differentiation potential—perspectives and therapeutic applications [J].
Sabine Hombach-Klonisch ;
Soumya Panigrahi ;
Iran Rashedi ;
Anja Seifert ;
Esteban Alberti ;
Paola Pocar ;
Maciej Kurpisz ;
Klaus Schulze-Osthoff ;
Andrzej Mackiewicz ;
Marek Los .
Journal of Molecular Medicine, 2008, 86 :1301-1314
[49]   Regulation of viability, differentiation and death of human melanoma cells carrying neural stem cell biomarkers: a possibility for neural trans-differentiation [J].
Ivanov, Vladimir N. ;
Hei, Tom K. .
APOPTOSIS, 2015, 20 (07) :996-1015
[50]   Hydrogen sulfide facilitates reprogramming and trans-differentiation in 3D dermal fibroblast [J].
Ostrakhovitch, Elena A. ;
Akakura, Shin ;
Tabibzadeh, Siamak .
PLOS ONE, 2020, 15 (11)
12345