Mitochondrial DNA haplogrouping of the Okhotsk people based on analysis of ancient DNA: an intermediate of gene flow from the continental Sakhalin people to the Ainu

被引:41
作者
Sato, Takehiro
Amano, Tetsuya [2 ]
Ono, Hiroko [2 ]
Ishida, Hajime [3 ]
Kodera, Haruto [4 ]
Matsumura, Hirofumi [5 ]
Yoneda, Minoru [6 ]
Masuda, Ryuichi [1 ]
机构
[1] Hokkaido Univ, Grad Sch Sci, Dept Nat Hist Sci, Kita Ku, Sapporo, Hokkaido 0600810, Japan
[2] Hokkaido Univ Museum, Sapporo, Hokkaido 0600810, Japan
[3] Univ Ryukyus, Fac Med, Dept Anat, Nishihara, Okinawa 9030215, Japan
[4] Tsurumi Univ, Sch Dent Med, Yokohama, Kanagawa 2308501, Japan
[5] Sapporo Med Univ, Dept Anat, Sapporo, Hokkaido 0608556, Japan
[6] Univ Tokyo, Grad Sch Frontier Sci, Kashiwa, Chiba 2778562, Japan
基金
日本学术振兴会;
关键词
Okhotsk people; genetic origins; ancient DNA; mitochondrial DNA; haplogroup; NONMETRIC CRANIAL VARIATION; HUMAN SKELETAL REMAINS; PHYLOGENETIC ANALYSIS; SEQUENCE; POLYMORPHISMS; POPULATIONS; LINEAGES; JAPANESE; ORIGINS; REGION;
D O I
10.1537/ase.081202
中图分类号
Q98 [人类学];
学科分类号
030303 ;
摘要
In order to further understand the genetic status of the Okhotsk people, who were distributed in southern coastal regions of the Okhotsk Sea during the 5th-13th centuries, nucleotide variations in the hypervariable region (HVR) and the coding regions of mitochondrial DNA (mtDNA) were analyzed. Targeting the coding regions provides reliable genetic information even from ancient DNAs that may have suffered post-mortem damage. MtDNA haplogroups of 38 individuals were classified according to mtDNA lineages known in northeastern Asian people. Comparisons of mtDNA haplogroup frequencies between the Okhotsk people and other Asian populations revealed that the genetic structures of the Okhotsk people are very similar to those of populations currently living around lower regions of the Amur River and the Ainu of Hokkaido. The results support our previous Study on molecular phylogeny of mtDNA HVR I sequences, and strongly suggest that the Okhotsk people originated around the lower regions of the Amur River and became an intermediate of gene flow from the continental Sakhalin people to the Ainu.
引用
收藏
页码:171 / 180
页数:10
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