Initial Single-center Experience of PIPAC in Patients With Unresectable Peritoneal Metastasis

被引:1
作者
Cuadrado Ayuso, Marta [1 ]
Cabanas Montero, Jacobo [1 ]
Priego Jimenez, Pablo [1 ]
Corral Moreno, Sara [1 ]
Longo Munoz, Federico [2 ]
Pachon Olmos, Vanesa [2 ]
Fernandez Cebrian, Jose Maria [1 ]
Galindo Alvarez, Julio [1 ]
机构
[1] Hosp Univ Ramon y Cajal, Cirugia Gen & Aparato Digest, Madrid, Spain
[2] Hosp Univ Ramon y Cajal, Oncol Med, Madrid, Spain
来源
CIRUGIA ESPANOLA | 2021年 / 99卷 / 05期
关键词
PIPAC; Peritoneal carcinomatosis; Intraperitoneal chemotherapy; Laparoscopy; INTRAPERITONEAL AEROSOL CHEMOTHERAPY; CYTOREDUCTIVE SURGERY; CARCINOMATOSIS; MANAGEMENT; DOXORUBICIN; SURVIVAL; CANCER;
D O I
10.1016/j.ciresp.2020.06.020
中图分类号
R61 [外科手术学];
学科分类号
摘要
Introduction: Peritoneal carcinomatosis remains a condition with poor prognosis and limited therapeutic options. Pressurized Intrapertioneal Aerosol Chemotherapy (PIPAC) has been developed as a new tool for delivering intraperitoneal chemotherapy with low morbidity. The aim of this study was to evaluate the initial experience of PIPAC in patients with peritoneal carcinomatosis at our hospital. Methods: A prospective study between January 2019 and February 2020 was carried at a tertiary public hospital. Primary tumor, ascites volume, PCI, chemotherapy regimen, operative time, morbidity, length of hospital stay and mortality were recorded for analysis. Results: We analyzed 9 PIPAC procedures performed in 5 patients. Median PCI was 27.6 (24-35). Median surgical time was 93 minutes (70-125). Only one adverse event occurred out of 9 procedures (Clavien-Dindo II). Median length of hospital stay was 2 days (1-4). Mortality was 0%. Conclusion: PIPAC seems to be a feasible and safe procedure to treat peritoneal carcinomatosis, with low morbidity and short hospital stay. (C) 2020 AEC. Published by Elsevier Espana, S.L.U. All rights reserved.
引用
收藏
页码:354 / 360
页数:7
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