Evidence of hepatitis E virus infection in specific pathogen-free rabbits in Korea

被引：8
作者：
Han, Sang-Hoon [1 ]
Park, Byung-Joo [1 ]
Ahn, Hee-Seop [1 ]
Kim, Yong-Hyun [1 ]
Go, Hyeon-Jeong [1 ]
Kim, Dong-Hwi [1 ]
Lee, Joong-Bok [1 ]
Park, Seung-Yong [1 ]
Song, Chang-Seon [1 ]
Lee, Sang-Won [1 ]
Choi, In-Soo [1 ]
机构：
[1] Konkuk Univ, Dept Infect Dis, Coll Vet Med, 120 Neungdong Ro, Seoul 05029, South Korea
来源：
VIRUS GENES | 2018年 / 54卷 / 04期
关键词：
Hepatitis E virus; Specific pathogen-free rabbit; RNA; Antibody; FARMED RABBITS; TRANSMISSION; CHINA; HUMANS; FRANCE;
D O I：
10.1007/s11262-018-1562-3
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Rabbits are considered a new natural reservoir of hepatitis E virus (HEV). In this study, HEV infection was verified by the detection of partial genomic sequence of HEV and anti-HEV antibodies in specific pathogen-free (SPF) rabbits. HEV RNA was found in 6.4% serum and 13.5% fecal samples from 126 SPF rabbits. Anti-HEV antibodies were also detected in 4.0% of the SPF rabbits. HEV genetic sequences isolated from the rabbits were clustered into a rabbit HEV clade with other rabbit HEV isolates; they were found to be most closely related with a rabbit HEV sequence previously reported in Korea. Therefore, HEV infection should be diagnosed before conducting experiments involving SPF rabbits.
引用
收藏
页码：587 / 590
页数：4
相关论文
共 19 条
  • [1] Rabbit Hepatitis E Virus Infections in Humans, France
    Abravanel, Florence
    Lhomme, Sebastien
    El Costa, Hicham
    Schvartz, Betoul
    Peron, Jean-Marie
    Kamar, Nassim
    Izopet, Jacques
    [J]. EMERGING INFECTIOUS DISEASES, 2017, 23 (07) : 1191 - 1193
  • [2] Prevalence and genetic features of rabbit hepatitis E virus in Korea
    Ahn, Hee-Seop
    Park, Byung-Joo
    Han, Sang-Hoon
    Kim, Yong-Hyun
    Kim, Dong-Hwi
    Kim, Bo-Sook
    Lee, Joong-Bok
    Park, Seung-Yong
    Song, Chang-Seon
    Lee, Sang-Won
    Choi, In-Soo
    [J]. JOURNAL OF MEDICAL VIROLOGY, 2017, 89 (11) : 1995 - 2002
  • [3] Hepatitis E Antibodies in Laboratory Rabbits from 2 US Vendors
    Birke, Leslie
    Cormier, Stephania A.
    You, Dahui
    Stout, Rhett W.
    Clement, Christian
    Johnson, Merlin
    Thompson, Hilary
    [J]. EMERGING INFECTIOUS DISEASES, 2014, 20 (04) : 693 - 696
  • [4] Hepatitis E Virus in Farmed Rabbits, Wild Rabbits and Petting Farm Rabbits in the Netherlands
    Burt, Sara A.
    Veltman, Jorg
    Hakze-van der Honing, Renate
    Schmitt, Heike
    van der Poel, Wim H. M.
    [J]. FOOD AND ENVIRONMENTAL VIROLOGY, 2016, 8 (03) : 227 - 229
  • [5] Hepatitis E Virus: First Description in a Pet House Rabbit. A New Transmission Route for Human?
    Caruso, C.
    Modesto, P.
    Prato, R.
    Scaglione, F. E.
    De Marco, L.
    Bollo, E.
    Acutis, P. L.
    Masoero, L.
    Peletto, S.
    [J]. TRANSBOUNDARY AND EMERGING DISEASES, 2015, 62 (03) : 229 - 232
  • [6] Hepatitis E Virus in Rabbits, Virginia, USA
    Cossaboom, Caitlin M.
    Cordoba, Laura
    Dryman, Barbara A.
    Meng, Xiang-Jin
    [J]. EMERGING INFECTIOUS DISEASES, 2011, 17 (11) : 2047 - 2049
  • [7] The role of hepatitis E virus testing in drug-induced liver injury
    Dalton, H. R.
    Fellows, H. J.
    Stableforth, W.
    Joseph, M.
    Thurairajah, P. H.
    Warshow, U.
    Hazeldine, S.
    Remnarace, R.
    Ijaz, S.
    Hussaini, S. H.
    Bendall, R. P.
    [J]. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2007, 26 (10) : 1429 - 1435
  • [8] Chronic hepatitis E: a review of the literature
    Fujiwara, S.
    Yokokawa, Y.
    Morino, K.
    Hayasaka, K.
    Kawabata, M.
    Shimizu, T.
    [J]. JOURNAL OF VIRAL HEPATITIS, 2014, 21 (02) : 78 - 89
  • [9] Hepatitis E Virus Strains in Rabbits and Evidence of a Closely Related Strain in Humans, France
    Izopet, Jacques
    Dubois, Martine
    Bertagnoli, Stephane
    Lhomme, Sebastien
    Marchandeau, Stephane
    Boucher, Samuel
    Kamer, Nassim
    Abravanel, Florence
    Guerin, Jean-Luc
    [J]. EMERGING INFECTIOUS DISEASES, 2012, 18 (08) : 1274 - 1281
  • [10] Molecular analysis of hepatitis E virus from farm rabbits in Inner Mongolia, China and its successful propagation in A549 and PLC/PRF/5 cells
    Jirintai, Suljid
    Jinshan
    Tanggis
    Manglai, Dugarjavin
    Mulyanto
    Takahashi, Masaharu
    Nagashima, Shigeo
    Kobayashi, Tominari
    Nishizawa, Tsutomu
    Okamoto, Hiroaki
    [J]. VIRUS RESEARCH, 2012, 170 (1-2) : 126 - 137
12