Control of Adult Stem Cell Behavior with Biomaterials

被引：14

作者：

Kim, Soojin ^{[1
,2
]}

Kim, Byung-Soo ^{[2
,3
]}

机构：

[1] Univ Alabama Birmingham, Dept Biomed Engn, Birmingham, AL 35294 USA

[2] Seoul Natl Univ, Sch Chem & Biol Engn, Seoul 151744, South Korea

[3] Seoul Natl Univ, Interdisciplinary Program Bioengn, Seoul 151744, South Korea

来源：

TISSUE ENGINEERING AND REGENERATIVE MEDICINE | 2014年 / 11卷 / 06期

基金：

新加坡国家研究基金会;

关键词：

adult stem cells; carbon nanomaterials; conductive gold nanoparticles; ECM; hydrogel; micropatterned surface; nanofibers; nanotopography; OSTEOGENIC DIFFERENTIATION; BONE; PROMOTE; NANOSCALE; STIFFNESS; BETA; TOPOGRAPHY; HYDROGELS; SURFACES; THERAPY;

D O I：

10.1007/s13770-014-0068-x

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Interactions of stem cells with biophysics of extracellular matrix (ECM) have shown a significant influence in control of the stem cell behavior. To mimic nanometer and micrometer scale of ECM structures, biomaterials such as nanotopographical substrates, nanofibers, conductive gold nanoparticles, carbon nanomaterials, hydrogels, and micropatterned surface are used to culture stem cells. In this review, we focused on easily attainable and clinically applied adult stem cells rather than embryonic stem cells and induced pluripotent stem cells that are still in infantile stage of research. We present the effects of the biomaterials on adult stem cell behavior, especially on stem cell differentiation.

引用

页码：423 / 430

页数：8

共 56 条

[1] Nanoscale topography of the basement membrane underlying the corneal epithelium of the rhesus macaque [J].