Ligands for glutamate receptors:: Design and therapeutic prospects

被引:524
作者
Bräuner-Osborne, H
Egebjerg, J
Nielsen, EO
Madsen, U
Krogsgaard-Larsen, P
机构
[1] Royal Danish Sch Pharm, Dept Med Chem, NeuroSci PharmaBiotec Res Ctr, DK-2100 Copenhagen, Denmark
[2] Aarhus Univ, Dept Mol & Struct Biol, DK-8000 Aarhus, Denmark
[3] NeuroSearch AS, Dept Neurochem, DK-2750 Ballerup, Denmark
关键词
D O I
10.1021/jm000007r
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
[No abstract available]
引用
收藏
页码:2609 / 2645
页数:37
相关论文
共 418 条
[51]   CLONING AND CHARACTERIZATION OF AN EXTRACELLULAR CA2+-SENSING RECEPTOR FROM BOVINE PARATHYROID [J].
BROWN, EM ;
GAMBA, G ;
RICCARDI, D ;
LOMBARDI, M ;
BUTTERS, R ;
KIFOR, O ;
SUN, A ;
HEDIGER, MA ;
LYTTON, J ;
HEBERT, SC .
NATURE, 1993, 366 (6455) :575-580
[52]  
BUCHAN A, 1990, J NEUROSCI, V10, P311
[53]  
BUCHAN AM, 1990, CEREBROVAS BRAIN MET, V2, P1
[54]  
BULLER AL, 1994, J NEUROSCI, V14, P5471
[55]   Characterization of [3H]-(2S,2′R,3′R)-2-(2′,3′-dicarboxycyclopropyl)glycine ([3H]-DCG IV) binding to metabotropic mGlu2 receptor-transfected cell membranes [J].
Cartmell, J ;
Adam, G ;
Chaboz, S ;
Henningsen, R ;
Kemp, JA ;
Klingelschmidt, A ;
Metzler, V ;
Monsma, F ;
Schaffhauser, H ;
Wichmann, J ;
Mutel, V .
BRITISH JOURNAL OF PHARMACOLOGY, 1998, 123 (03) :497-504
[56]   Overexpression of a glutamate receptor (GluR2) ligand binding domain in Escherichia coli: Application of a novel protein folding screen [J].
Chen, GQ ;
Gouaux, E .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (25) :13431-13436
[57]   Differential sensitivity of recombinant N-methyl-D-aspartate receptor subtypes to zinc inhibition [J].
Chen, NS ;
Moshaver, A ;
Raymond, LA .
MOLECULAR PHARMACOLOGY, 1997, 51 (06) :1015-1023
[58]  
Chenard BL, 1999, CURR PHARM DESIGN, V5, P381
[59]   Kainate receptors: subunits, synaptic localization and function [J].
Chittajallu, R ;
Braithwaite, SP ;
Clarke, VRJ ;
Henley, JM .
TRENDS IN PHARMACOLOGICAL SCIENCES, 1999, 20 (01) :26-35
[60]   Regulation of glutamate release by presynaptic kainate receptors in the hippocampus [J].
Chittajallu, R ;
Vignes, M ;
Dev, KK ;
Barnes, JM ;
Collingridge, GL ;
Henley, JM .
NATURE, 1996, 379 (6560) :78-81